314767-75-4

Basic information

• Product Name: 2,7-DIAMINO-4-PYRIDIN-3-YL-4H-CHROMENE-3-CARBONITRILE
• Synonyms: 2,7-DIAMINO-4-PYRIDIN-3-YL-4H-CHROMENE-3-CARBONITRILE;AKOS UB-20644;TIMTEC-BB SBB007452
• CAS NO: 314767-75-4
• Molecular Formula: C15H12N4O
• Molecular Weight: 264.28
• Mol File: 314767-75-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,7-DIAMINO-4-PYRIDIN-3-YL-4H-CHROMENE-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,7-DIAMINO-4-PYRIDIN-3-YL-4H-CHROMENE-3-CARBONITRILE(314767-75-4)
• EPA Substance Registry System: 2,7-DIAMINO-4-PYRIDIN-3-YL-4H-CHROMENE-3-CARBONITRILE(314767-75-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 314767-75-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,7-DIAMINO-4-PYRIDIN-3-YL-4H-CHROMENE-3-CARBONITRILE is used as a key intermediate in the synthesis of various drugs for its potential biological activities.
Used in Medicinal Chemistry Research:
2,7-DIAMINO-4-PYRIDIN-3-YL-4H-CHROMENE-3-CARBONITRILE is used as a subject of study for its potential applications in developing new drugs with anti-inflammatory, antitumor, and antiviral properties.

Upstream product

• 500-22-1 3-pyridinecarboxaldehyde 
• 591-27-5 m-Hydroxyaniline 
• 109-77-3 malononitrile 

Relevant articles and documents

Substituted 4H-chromenes and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 4H-chromenes and analogs thereof, represented by the general Formula I: 1wherein R1-R5, A, Y and Z are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention can be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.

One-step synthesis of substituted 2-amino-4H-chromenes and 2-amino-4H-benzo[f]chromenes. Molecular and crystal structure of 2-amino-3-cyano-6-hydroxy-4-phenyl-4H-benzo[f]chromene

Substituted 2-aminochromenes were synthesized by three-component condensation of aromatic aldehydes, derivatives of cyanoacetic acid, and phenols or naphthols. The molecular and crystal structure of 2-amino-3-cyano-6-hydroxy-4-phenyl-4H-benzo[f]chromene w