- Derivatives of pyrazole-5-acetic acid
-
Compounds having anti-inflammatory and antipyretic action have the general formula SPC1 In which each of R1 and R2 is a phenyl group which may be substituted by a halogen atom, an alkyl or alkoxy group having 1 to 4 carbon atoms or a trifluoromethyl group, R3 is a straight or branched chain saturated or unsaturated aliphatic hydrocarbon group or a cycloaliphatic hydrocarbon group having 3 to 7 carbon atoms, or a benzyl or phenyl group which benzyl or phenyl groups may be substituted in the benzene ring by a halogen atom, an alkyl or alkoxy group having 1 to 4 carbon atoms or a trifluoromethyl group or by any two of these substituents, R4 is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms and A is a group having one of the formulae --COOH, --COOR5 and --CONR6 R7 in which R5 is an alkyl group having 1 to 4 carbon atoms or a benzyl group and each of R6 and R7 is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms or R6 and R7 taken together with the nitrogen atom to which they are attached represents a pyrrolidino, a piperidino or a morpholino group.
- -
-
-