- Sodium lauryl sulfate-catalyzed oxidative chlorination of aromatic compounds
-
Chlorination of commercially important aromatic compounds using sodium chloride as chlorine source and sodium periodate as oxidant in acidic medium catalyzed by sodium lauryl sulfate (SLS) led to the chloro-substituted aromatics in good yields and purity. Addition of sodium lauryl sulfate led to increased chlorination rate, better yield, excellent purity, and better quality of end product. The advantages of the present method are greater yield, excellent purity, and shorter reaction time at room temperature. Also dichlorinated product can be obtained by increasing the amount of sodium chloride and sodium periodate at slightly higher temperature (40C).
- Mahajan, Tanu,Kumar, Lalit,Dwivedi, K.,Agarwal, D. D.
-
p. 3655 - 3663,9
(2020/08/31)
-
- INHIBITORS OF STEAROYL-COA DESATURASE
-
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity.
- -
-
-
- Acyl derivatives of 2-aminobenzimidazole and their fungicide activity
-
Procedures have been developed for the preparation of methyl 2-benzimidazolylcarbamate, 2-acetylaminobenzimidazole, 2- benzoylaminobenzimidazole, 2-(3,5-dibromo-2-hydroxybenzoylamino)benzimidazole, 1-(3,6-dichloro-2-methoxybenzoyl)-2-aminobenzimidazole, 2-(3,5-dichloro-2- hydroxybenzoylamino)benzimidazole, 2-(3,5-dichloro-2-methoxybenzoylamino) benzimidazole, and 1-(3,5,6-trichloro-2-methoxybenzoyl)-2-aminobenzimidazole. The synthesized compounds have been tested for fungicide activity.
- Pilyugin,Sapozhnikov,Sapozhnikova
-
p. 738 - 743
(2007/10/03)
-
- Mild chlorination of aromatic compounds with tin(IV) chloride and lead tetraacetate
-
SnCl4/Pb(OAc)4 acts as a safe source of Cl2 for the chlorination of aromatic compounds. A variety of aromatic compounds are effectively chlorinated with SnCl4/Pb(OAc)4 under mild conditions. The mixture is a selective chlorinating agent, particularly with polyalkylbenzenes, polycyclic aromatic compounds and anisoles.
- Muathen, Hussni A.
-
p. 8863 - 8866
(2007/10/03)
-
- Some Observations on Chlorination of Salicylic Acid and Its 5-Sulphonic Acid Derivative
-
Chlorination of salicylic acid with t-butyl hypochlorite in CCl4 affords only 5-chlorosalicylic acid and not 3-chloro isomer as reported earlier.Direct chlorination of 5-sulphosalicylic acid in acetic acid yields 3,5-dichlorosalicylic acid besides the sulphonated product, showing that SO3H group undergoes electrophilic displacement by Cl+.
- Jain, A. C.,Gupta, S. K.,Bambah, P. K.
-
p. 575 - 576
(2007/10/02)
-
- Synthesis and Evaluation of Diaryl Oxalate Esters for Low-Intensity Chemiluminescent Illumination
-
Various diaryl oxalate esters have been prepared from oxalyl chloride and substituted salicylates.A number of intermediates and byproducts were obtained from chlorinations of salicylic acid and their mechanistic significance has been discussed.The chemiluminescent emission from the oxalates in the presence of hydrogen peroxide has been examined in the search for low-intensity illumination of at least 10 h duration.Bis(2-alkoxycarbonyl-4,6-dinitrophenyl) oxalates were too unstable while the chemiluminescence of the bis(6-alkoxycarbonyl-2,4,5-trichlorophenyl) oxalates c ould not be adjusted suitably.Some bis(6-alkoxycarbonyl-2,4-dichlorophenyl) oxalates were prepared and, by treatment with various combinations of potassium salicylate and oxalic acid, satisfactory low-intensity light emission could be achieved.
- Dowd, Christopher D.,Paul, D. Brenton
-
-
- Dual Fluorescence and Ground State Equilibria in Methyl Salicylate, Methyl 3-Chlorosalicylate, and Methyl 3-tert-Butylsalicylate
-
Fluorescence spectra of methyl 3-chlorosalicylate, methyl 3-tert-butylsalicylate, and o-hydroxyacetophenone in cyclohexane and ethanol at room temperature have been measured, together with the corrected dual fluorescence excitation spectra of gas-phase methyl salicylate.Based on these observations a ground state equilibrium between two tautomers is proposed, both having an intramolecular hydrogen bond.This model is consistent with a number of methyl salicylate H-bond energy estimates.It also allowed an interpretation of the multiple fluorescence emitted from these and related compounds either in solution or in gas phase.
- Acuna, A. U.,Amat-Guerri, F.,Catalan, J.,Gonzalez-Tablas, F.
-
p. 629 - 631
(2007/10/02)
-