The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA
Family ties: The AlkB family of nonheme iron, α-ketoglutarate (αKG)-dependent dioxygenases is involved in biological processes such as DNA/RNA repair and obesity. The AlkB domain of ABH8 is shown to catalyze the hydroxylation of a modified uridine (mcmsu
Synthesis and Biophysical Characterization of tRNALys,3 Anticodon Stem-loop RNAs Containing the mcm5s2U Nucleoside
equation presented Phosphoramidite reagents of the naturally occurring modified nucleosides mcm5s2U and mcm5U were synthesized and along with pseudouridine were incorporated into 17-nucleotide lysine tRNA anticodon stem-lo
Bajji, Ashok C.,Davis, Darrell R.
p. 3865 - 3868
(2007/10/03)
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