324076-69-9

Basic information

• Product Name: 1-(4-(TRIFLUOROMETHYL)PHENETHYL)-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE
• Synonyms: 1-(4-(TRIFLUOROMETHYL)PHENETHYL)-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE;1-[2-(4-Trifluoromethylphenyl)ethyl]-6,7-dimethoxy-3,4-dihydroisoquinoline
• CAS NO: 324076-69-9
• Molecular Formula: C20H20F3NO2
• Molecular Weight: 363.37
• Mol File: 324076-69-9.mol

Chemical Properties

• Boiling Point: 448°C at 760 mmHg
• Flash Point: 224.8°C
• Appearance: /
• Density: 1.21g/cm³
• Vapor Pressure: 8.49E-08mmHg at 25°C
• Refractive Index: 1.532
• CAS DataBase Reference: 1-(4-(TRIFLUOROMETHYL)PHENETHYL)-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(TRIFLUOROMETHYL)PHENETHYL)-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE(324076-69-9)
• EPA Substance Registry System: 1-(4-(TRIFLUOROMETHYL)PHENETHYL)-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE(324076-69-9)

Safety Data

• Hazardous Substances Data: 324076-69-9(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry Research:
1-(4-(TRIFLUOROMETHYL)PHENETHYL)-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE is used as a research compound for exploring its potential pharmacological properties and applications in medicinal chemistry.
Used in Drug Development:
1-(4-(TRIFLUOROMETHYL)PHENETHYL)-6,7-DIMETHOXY-3,4-DIHYDROISOQUINOLINE is utilized in drug development processes to investigate its therapeutic potential and identify possible applications in treating various diseases or conditions.

InChI:InChI=1/C20H20F3NO2/c1-25-18-11-14-9-10-24-17(16(14)12-19(18)26-2)8-5-13-3-6-15(7-4-13)20(21,22)23/h3-4,6-7,11-12H,5,8-10H2,1-2H3

Upstream product

• 1169801-38-0 6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-3,4-dihydro-isoquinoline hydrochloride 
• 1169801-32-4 6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-3,4-dihydro-isoquinoline methanesulfonic acid salt 
• 769172-66-9 N-[2-(3,4-dimethoxy-phenyl)-ethyl]-3-(4-trifluoromethyl-phenyl)-propionamide 

Downstream Products

• 1228803-88-0 (R)-6,7-dimethoxy-1-(4-(trifluoromethyl)phenethyl)-1,2,3,4-tetrahydroisoquinoline 
• 769172-81-8 (S)-6,7-dimethoxy-1-(4-(trifluoromethyl)phenethyl)-1,2,3,4-tetrahydroisoquinoline 
• 1260118-25-9 6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-3,4-dihydro-1H-isoquinoline-2-carbaldehyde 

Relevant articles and documents

METHOD FOR OBTAINING AN OPTICALLY PURE 1,2,3,4 TETRAHYDRO-ISOQUINOLINE DERIVATIVE

The invention relates to a method for obtaining enantiomerically enriched 6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-1,2,3,4-tetrahydro-isoquinoline from a mixture of (R)-6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-1,2,3,4-tetrahydro-isoquinoline and (S)-6,7-dimethoxy-1-[2-(4-trifluoromethyl-phenyl)-ethyl]-1,2,3,4-tetrahydro-isoquinoline.

TRISUBSTITUTED 3,4-DIHYDRO-1H-ISOQUINOLIN COMPOUND, PROCESS FOR ITS PREPARATION, AND ITS USE

The present invention relates to the compound of formula 7*acetate (see below), a process for its preparation, and its use

PROCESS FOR THE PREPARATION OF AN ENANTIOMERIC TRISUBSTITUTED 3,4-DIHYDRO-ISOQUINOLINE DERIVATIVE

The present invention relates to a process for the preparation of the compound of formula (7) which process comprises the hydrogenation of the compound of formula (4) using bis[chloro-1,5-cyclooctadiene-iridium], (S)-i-dicyclohexylphosphino-2-[(S)-α-(dime

PROCESS FOR THE PREPARATION OF AN ENANTIOMERIC TRISUBSTITUTED 3,4-DIHYDRO-ISOQUINOLINE DERIVATIVE

The present invention relates to a process for the preparation of the compound of formula (7) which process comprises the hydrogenation of the compound of formula (4) using bis[chloro-1,5-cyclooctadiene-iridium], (S)-i -dicyclohexylphosphino- 2-[(S)-α-(di

TRISUBSTITUTED 3,4-DIHYDRO-1H-ISOQUINOLIN COMPOUND, PROCESS FOR ITS PREPARATION, AND ITS USE

The present invention relates to the compound of formula (7*)acetate (see below), a process for its preparation, and its use.

SUBSTITUTED 1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES

The invention relates to novel 1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) wherein R1, R2, R3 and X are as defined in the claims, and their use as active ingredients in the preparation of pharmaceutical compo

TETRAHYDROISOQUINOLYL ACETAMIDE DERIVATIVES FOR USE AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to novel acetamide derivatives of formula (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of such compound