- Synthesis of 1,3,4,6-tetraoxo compounds
-
The two-step method of synthesis of 1,3,4,6-tetraoxocompounds with different terminal substituents is developed. By condensation of alkyl methyl ketones with dimethyl oxalate new 1,6-dialkyl-substituted 1,3,4,6-tetraoxohexanes are obtained. The esters of 3,4,6-trioxoalkanoic acids are synthesized by the condensation reaction of alkyl acetates with dialkyl oxalates and alkyl methyl ketones. By the reaction of ethyl acetate with diethyl oxalate and methyl acetate the mixed diester of 3,4-dioxo-1,6-hexanedioic (ketipic) acid has been first prepared. Specific structural features of the synthesized compounds are discussed basing on the data of the IR, NMR, and XRD diffraction (XRD) analysis.
- Mukovoz,Koz’minykh,Gorbunova,Slepukhin,El’tsov,Ganebnykh,Kuzmin
-
-
Read Online
- A novel synthesis of imidazo [4,5-d] azepine Ring System
-
A novel synthesis of imidazo[4,5-d]azepine 5 from α-diketone is described. This is achieved either via acyloin condensation of the diester 3 followed by addition of trimethylsilylchloride or by condensation of the azepino-diketone 7 with S-methylisothiour
- Waly,Said,Ayyad
-
p. 296 - 301
(2007/10/03)
-