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TYLOPHORIDICINE A(), 98+% is a recently discovered Tylophora alkaloid found in the roots of T. asthmatica. It is characterized by its optical rotation of [α]25D + 108° (c 1.91, MeOH) and its ultraviolet spectrum in MeOH with absorption maxima at 258, 286.5, 310, 339.5, and 355 Mu. TYLOPHORIDICINE A(), 98+% contains two methoxyl groups and two phenolic hydroxyl groups, and it can be converted into its O,O-dimethyl ether (m.p. 218-220°C) and diacetate (m.p. 192°C) derivatives.

32523-69-6

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32523-69-6 Usage

Uses

Used in Pharmaceutical Industry:
TYLOPHORIDICINE A(), 98+% is used as a biological study compound for thymidylate synthase in leukocytes from patients with chronic myelocytic leukemia and acute lymphocytic leukemia. It serves as an inhibitor of pergularinine and tylophorinidine, playing a crucial role in the development of potential therapeutic strategies for these types of leukemia.
Used in Research and Development:
TYLOPHORIDICINE A(), 98+% is utilized in research and development for its potential applications in the pharmaceutical and biotechnology industries. Its unique chemical properties and biological activities make it a valuable compound for further investigation and potential drug development.

References

Mulchandani, Iyer, Badheka., Chem. Ind., 505 (1971)

Check Digit Verification of cas no

The CAS Registry Mumber 32523-69-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,5,2 and 3 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 32523-69:
(7*3)+(6*2)+(5*5)+(4*2)+(3*3)+(2*6)+(1*9)=96
96 % 10 = 6
So 32523-69-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H23NO4/c1-26-12-5-6-13-14(8-12)15-9-19(24)20(27-2)10-16(15)17-11-23-7-3-4-18(23)22(25)21(13)17/h5-6,8-10,18,22,24-25H,3-4,7,11H2,1-2H3/t18-,22+/m1/s1

32523-69-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (13aS,14S)-3,7-dimethoxy-9,11,12,13,13a,14-hexahydrophenanthro[10,9-f]indolizine-6,14-diol

1.2 Other means of identification

Product number -
Other names Tylophorinidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32523-69-6 SDS

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