325486-37-1

Basic information

• Product Name: N-Benzyl-3-(tert-butyldimethylsilanyloxymethyl)piperid-4-one
• Synonyms: N-Benzyl-3-(tert-butyldimethylsilanyloxymethyl)piperid-4-one;1-Benzyl-3-[(tert-butyldimethylsilyloxy)methyl]piperidin-4-one;N-Benzyl 3-(tert-butyl-dimethyl-silanyloxymethyl)-piperidin-4-one;1-Benzyl-3-[(tert-butyldimethylsilyloxy)methyl]piperidin-4-one 95%;N-BENZY 3-(TERT-BUTYLDIMETHYLSILANYLOXYMETHYL)PIPERID-4-ONE;1-Benzyl-3-{[(tert-butyldimethylsilyl)oxy]methyl}-4-oxopiperidine,[(1-Benzyl-4-oxopiperidin-3-yl)methoxy]tert-butyldimethylsilane;1-Benzyl-3-({[(tert-butyl)dimethylsilyl]oxy}methyl)piperidin-4-one95%;3-[[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]METHYL]-1-(PHENYLMETHYL)-4-PIPERIDINONE
• CAS NO: 325486-37-1
• Molecular Formula: C₁₉H₃₁NO₂Si
• Molecular Weight: 333.54044
• Mol File: 325486-37-1.mol

Chemical Properties

• Boiling Point: 397.685 °C at 760 mmHg
• Flash Point: 194.313 °C
• Appearance: /
• Density: 0.997 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.503
• PKA: 6.63±0.40(Predicted)
• CAS DataBase Reference: N-Benzyl-3-(tert-butyldimethylsilanyloxymethyl)piperid-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzyl-3-(tert-butyldimethylsilanyloxymethyl)piperid-4-one(325486-37-1)
• EPA Substance Registry System: N-Benzyl-3-(tert-butyldimethylsilanyloxymethyl)piperid-4-one(325486-37-1)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 325486-37-1(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry Research:
N-Benzyl-3-(tert-butyldimethylsilanyloxymethyl)piperid-4-one is used as a research compound for exploring its pharmacological and biological activities. Its unique structure and properties make it a valuable candidate for the development of new drugs and therapeutic agents.
Used in Drug Development:
As a piperidone derivative with potential pharmacological activities, N-Benzyl-3-(tert-butyldimethylsilanyloxymethyl)piperid-4-one is used in the development of new drugs. Its structure and properties may contribute to the discovery of novel therapeutic agents with improved efficacy and safety profiles.
Used in Organic Synthesis:
N-Benzyl-3-(tert-butyldimethylsilanyloxymethyl)piperid-4-one is used as a building block in organic synthesis. Its unique structure allows for the creation of new chemical entities with potential applications in various fields, including pharmaceuticals, materials science, and agrochemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-Benzyl-3-(tert-butyldimethylsilanyloxymethyl)piperid-4-one is used as a key intermediate in the synthesis of various drug candidates. Its potential pharmacological activities and unique structure make it a valuable component in the development of innovative therapeutic agents.
Used in Chemical Research and Development:
N-Benzyl-3-(tert-butyldimethylsilanyloxymethyl)piperid-4-one is used in chemical research and development to explore its potential applications and effects. Further studies and research are needed to fully understand its properties and potential uses in various industries, including pharmaceuticals, materials science, and agrochemicals.

InChI:InChI=1/C19H31NO2Si/c1-19(2,3)23(4,5)22-15-17-14-20(12-11-18(17)21)13-16-9-7-6-8-10-16/h6-10,17H,11-15H2,1-5H3

Upstream product

• 214615-87-9 1-benzyl-3-hydroxymethyl-4-oxopiperidine 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 97692-42-7 1-Benzyl-4-piperidon-3-carbonsaeuremethylester 
• 64996-14-1 8-benzyl-1,4-dioxa-8-aza-spiro[4.5]decane-6-carboxylic acid methyl ester 
• 3939-01-3 methyl 1-benzyl-4-oxopiperidine-3-carboxylate hydrochloride 
• 64996-15-2 (8-benzyl-1,4-dioxa-8-aza-spiro[4.5]dec-6-yl)-methanol 

Relevant articles and documents

CYCLOALKANOPYRIDINE DERIVATIVE

Provided are cycloalkanopyridine derivatives of formula [I]: [wherein the symbols are the same as those stated in the description]. The compounds act as a nociceptin receptor antagonist, and are useful as medicines for diseases associated with a nociceptin receptor, for example, as a reliever against tolerance to a narcotic analgesic; a reliever against dependence on or addiction to a narcotic analgesic; an analgesic enhancer; an antiobesitic or appetite suppressor; a treating or prophylactic agent for cognitive impairment and dementia/amnesia; an agent for treating developmental cognitive abnormality; a remedy for schizophrenia; an agent for treating neurodegenerative diseases; an anti-depressant or treating agent for affective disorder; a treating or prophylactic agent for diabetes insipidus; a treating or prophylactic agent for polyuria; or a remedy for hypotension.

SEROTONERGIC BENZOFURANS

The present invention provides serotonergic benzofurans of Formula (I): where A, R, R, R, R, and R are as described in the specification.