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N-(3-acetylphenyl)-N-methylacetamide, commonly known as N-phenacemide, is a chemical compound with the molecular formula C11H13NO2. It is a white to off-white crystalline powder and a derivative of acetanilide. N-phenacemide has been studied for its potential as an analgesic and antipyretic agent, with inhibitory effects on prostaglandin synthesis. It has also been investigated for its potential use in treating conditions such as epilepsy and migraine headaches. However, its application has been limited due to concerns about its potential toxicity and side effects.

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  • 325715-13-7 Structure
  • Basic information

    1. Product Name: N-(3-ACETYLPHENYL)-N-METHYLACETAMIDE
    2. Synonyms: N-(3-ACETYLPHENYL)-N-METHYLACETAMIDE;N-(3-Acetylphenyl)-N-methylacetamide 98%;3(N-Methylacetamido)Acetophenone;N-(3-Acetylphenyl)-N-methylacetamide98%
    3. CAS NO:325715-13-7
    4. Molecular Formula: C11H13NO2
    5. Molecular Weight: 191.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 325715-13-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 330.7 °C at 760 mmHg
    3. Flash Point: 146.3 °C
    4. Appearance: /
    5. Density: 1.108 g/cm3
    6. Vapor Pressure: 0.000163mmHg at 25°C
    7. Refractive Index: 1.553
    8. Storage Temp.: Sealed in dry,Room Temperature
    9. Solubility: N/A
    10. CAS DataBase Reference: N-(3-ACETYLPHENYL)-N-METHYLACETAMIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: N-(3-ACETYLPHENYL)-N-METHYLACETAMIDE(325715-13-7)
    12. EPA Substance Registry System: N-(3-ACETYLPHENYL)-N-METHYLACETAMIDE(325715-13-7)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 325715-13-7(Hazardous Substances Data)

325715-13-7 Usage

Uses

Used in Pharmaceutical Industry:
N-(3-acetylphenyl)-N-methylacetamide is used as a potential analgesic and antipyretic agent for its ability to inhibit prostaglandin synthesis, which is associated with pain and fever reduction.
Used in Neurological Conditions Treatment:
In the field of neurology, N-phenacemide is used as a potential treatment for conditions such as epilepsy and migraine headaches, due to its effects on the central nervous system.
However, it is important to note that the use of N-(3-acetylphenyl)-N-methylacetamide is limited due to concerns about its potential toxicity and side effects, which may outweigh its therapeutic benefits in certain applications. Further research and development are necessary to fully understand its safety profile and optimize its use in medical treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 325715-13-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,5,7,1 and 5 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 325715-13:
(8*3)+(7*2)+(6*5)+(5*7)+(4*1)+(3*5)+(2*1)+(1*3)=127
127 % 10 = 7
So 325715-13-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO2/c1-8(13)10-5-4-6-11(7-10)12(3)9(2)14/h4-7H,1-3H3

325715-13-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(3-ACETYLPHENYL)-N-METHYLACETAMIDE

1.2 Other means of identification

Product number -
Other names 3'-acetyl-N-methylacetanilide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:325715-13-7 SDS

325715-13-7Relevant articles and documents

TETRAZOLINONE COMPOUND AND USE THEREOF

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, (2015/11/16)

The compound represented by formula (1): wherein R4 and R5 each represents a hydrogen atom, a halogen atom, or a C1-C3 alkyl group; R6 represents a C1-C4 alkyl group, a C3-C6 cycloalkyl group, or the like; R7, R8, and R9 each represents a hydrogen atom, a halogen atom, or the like; R10 represents a C1-C3 alkyl group, or the like; R13 represents a C1-C3 alkyl group, or the like; and Q represents a phenyl group, or the like; has an excellent control effect on pests.

Salts And Co-Crystals of Pyrazolopyrimidine Compounds, Compositions Thereof And Methods For Their Production And Use

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Page/Page column 10, (2010/11/30)

The invention provides pharmaceutically acceptable salts and co-crystals of pyrazolopyrimidine compounds such as zaleplon, indiplon and ocinaplon, processes for their preparation, compositions comprising such salts and co-crystals and methods of using such salts and co-crystals for treating various diseases and conditions.

PRODUCTION OF N-ALKYLAMIDE COMPOUNDS

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Page 17, (2008/06/13)

The present invention provides an efficient process for the production of N-acylaniline derivatives by selectively alkylating an amide group at the nitrogen atom. The process comprises reacting an amide compound of the formula (2): (wherein, R1 and R2 are each independently an alkyl group, a substituted alkyl group, an alkenyl group, a substituted alkenyl group, an aryl group or a substituted aryl group) with a sulfuric acid ester in the presence of a solid metal hydroxide to give an N-alkylamide compound of the formula (3): (wherein R3 is an alkyl group and R1 and R2 have each the same meaning as described above).

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