325773-65-7

Basic information

• Product Name: BIS(3,5-DI-TERT-BUTYLPHENYL)PHOSPHINE OXIDE
• Synonyms: BIS(3,5-DI-TERT-BUTYLPHENYL)PHOSPHINE OXIDE;Phosphine oxide,bis[3,5-bis(1,1-dimethylethyl)phenyl]-
• CAS NO: 325773-65-7
• Molecular Formula: C₂₈H₄₃OP
• Molecular Weight: 426.61
• Mol File: 325773-65-7.mol

Chemical Properties

• Boiling Point: 481.1±55.0 °C(Predicted)
• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: BIS(3,5-DI-TERT-BUTYLPHENYL)PHOSPHINE OXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(3,5-DI-TERT-BUTYLPHENYL)PHOSPHINE OXIDE(325773-65-7)
• EPA Substance Registry System: BIS(3,5-DI-TERT-BUTYLPHENYL)PHOSPHINE OXIDE(325773-65-7)

Safety Data

• Hazardous Substances Data: 325773-65-7(Hazardous Substances Data)

Upstream product

• 22385-77-9 1-bromo-3,5-di-tert-butylbenzene 
• 762-04-9 phosphonic acid diethyl ester 
• 762-04-9 Diethyl phosphonate 

Relevant articles and documents

Development of effective bidentate diphosphine ligands of ruthenium catalysts toward practical hydrogenation of carboxylic acids

Hydrogenation of carboxylic acids (CAs) to alcohols represents one of the most ideal reduction methods for utilizing abundant CAs as alternative carbon and energy sources. However, systematic studies on the effects of metal-to-ligand relationships on the catalytic activity of metal complex catalysts are scarce. We previously demonstrated a rational methodology for CA hydrogenation, in which CA-derived cationic metal carboxylate [(PP)M(OCOR)]+ (M = Ru and Re; P = one P coordination) served as the catalyst prototype for CA self-induced CA hydrogenation. Herein, we report systematic trial- and-error studies on how we could achieve higher catalytic activity by modifying the structure of bidentate diphosphine (PP) ligands of molecular Ru catalysts. Carbon chains connecting two P atoms as well as Ar groups substituted on the P atoms of PP ligands were intensively varied, and the induction of active Ru catalysts from precatalyst Ru(acac)3 was surveyed extensively. As a result, the activity and durability of the (PP)Ru catalyst substantially increased compared to those of other molecular Ru catalyst systems, including our original Ru catalysts. The results validate our approach for improving the catalyst performance, which would benefit further advancement of CA self-induced CA hydrogenation.

PROCESS FOR PREPARATION OF DIPHOSPHINE COMPOUNDS AND INTERMEDIATES FOR THE PROCESS

A production method of a_compound represented by the formula wherein R1a, R1b, R1c, R1d, R1e, R1f, R2a, R2b, R2c R2d, R2e and R2f are the same or different and each is a hydrogen atom and the like, and R3, R4, R5, R6, R7, R8, R9 and R10 are the same or different and each is a hydrogen atom and the like, or a salt thereof, which comprises reacting a compound represented by the formula wherein X is a leaving group and other symbols are as defined above, or a salt thereof, with a phosphine-borane complex represented by the formula wherein the symbols are as defined above, or a salt thereof, in a solvent in the presence of an amine and a nickel catalyst, is provided.