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328277-09-4

8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 328277-09-4 Structure

  • Basic information

    1. Product Name: 8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one
    2. Synonyms: 8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one;12-chloro-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,10,12-pentaen-6-one
    3. CAS NO:328277-09-4
    4. Molecular Formula: C10H5ClN2O2
    5. Molecular Weight: 220.62
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 328277-09-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one(328277-09-4)
    11. EPA Substance Registry System: 8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one(328277-09-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 328277-09-4(Hazardous Substances Data)

328277-09-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 328277-09-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,8,2,7 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 328277-09:
(8*3)+(7*2)+(6*8)+(5*2)+(4*7)+(3*7)+(2*0)+(1*9)=154
154 % 10 = 4
So 328277-09-4 is a valid CAS Registry Number.

328277-09-4Downstream Products

328277-09-4Relevant articles and documents

Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists

Cramp, Sue,Dyke, Hazel J.,Higgs, Christopher,Clark, David E.,Gill, Matthew,Savy, Pascal,Jennings, Neil,Price, Steve,Lockey, Peter M.,Norman, Dennis,Porres, Soraya,Wilson, Francis,Jones, Alison,Ramsden, Nigel,Mangano, Raffaella,Leggate, Dan,Andersson, Marie,Hale, Richard

scheme or table, p. 2516 - 2519 (2010/06/20)

The identification and hit-to-lead exploration of a novel, potent and selective series of histamine H4 receptor inverse agonists is described. The initial hit, 3A (IC50 19 nM) was identified by means of a ligand-based virtual screening approach. Subsequent medicinal chemistry exploration yielded 18I which possessed increased potency (R-enantiomer IC50 1 nM) as well as enhanced microsomal stability.

Pyrimidine compounds as histamine modulators

-

, (2008/06/13)

The present invention relates to novel pyrimidine compounds, for the modulation of the histamine H4 receptor and the treatment or prevention of conditions mediated by the histamine H4 receptor. The invention also relates to the preparation of such compoun

Pyrimidine compounds for the treatment of inflammatory disorders

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Page/Page column 12-13, (2010/11/26)

The present invention relates to novel pyrimidine compounds, for the modulation of the histamine H4 receptor and the treatment or prevention of conditions mediated by the histamine H4 receptor. The invention also relates to the preparation of such compoun

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