Enantioselective Rhodium(I)-Catalyzed Hydrogenation of Trifluoromethyl Ketones
(Matrix Presented) The asymmetric hydrogenation of trifluoromethyl ketones to yield chiral α-trifluoromethyl alcohols with enantiomeric excesses up to 98% was achieved in the presence of chiral rhodium-(amidephosphine-phosphinite) complexes.