One-pot syntheses of 6-mercaptopurines (6MP) from 4,5-diamino-6-chloro- pyrimidines
A one-pot synthesis of 6-mercaptopurines from 4,5-diamino-6-chloro- pyrimidine, an aldehyde and elemental sulfur is presented. The key advantage of this procedure is that it utilizes the in situ generated H2S to convert the chloro to a mercapto group.