32996-24-0 Usage
Uses
Used in Pharmaceutical Industry:
6-ISOPROPYLINDOLE 97 is used as a reactant for the preparation of potent and selective 5-HT7 receptor ligands. These ligands are crucial in the development of drugs targeting the 5-HT7 receptor, which is involved in various physiological processes and has been implicated in the treatment of conditions such as depression, anxiety, and schizophrenia.
Used in Chemical Synthesis:
6-ISOPROPYLINDOLE 97 is used as a reactant in triflic acid-catalyzed stereoselective Friedel-Crafts aminoalkylation reactions. This application is significant in the synthesis of complex organic molecules with specific stereochemistry, which is essential for the development of new drugs and other chemical products with desired biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 32996-24-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,9,9 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 32996-24:
(7*3)+(6*2)+(5*9)+(4*9)+(3*6)+(2*2)+(1*4)=140
140 % 10 = 0
So 32996-24-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N/c1-8(2)10-4-3-9-5-6-12-11(9)7-10/h3-8,12H,1-2H3
32996-24-0Relevant articles and documents
REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS
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Paragraph 00361; 00364-00365; 00893; 00896-00897, (2022/01/05)
The present disclosure provides compounds of Formula IA and Formula IB and their pharmaceutical compositions as selective agonists of REV-ERB-α: where R1, R2, R3, R4, R5, RX1, RX2, nA, nB, X, Y, and Z are described herein. The compounds are useful in various methods and uses, such as in the treatment of diseases including hyperglycemia, dyslipidemia, atherosclerosis, and autoimmune and inflammatory disorders or diseases, and as cancer therapeutics, such as for the treatment of glioblastoma, hepatocellular carcinoma, and colorectal cancer, and for immune-oncology purposes.
Intermediates for indoles
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, (2008/06/13)
Ortho-nitrotoluenes are condensed with formamide acetals to yield the corresponding otho-nitro-β-aminestyrenes which undergo cyclization upon reduction to yield indoles.
