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1-[(1H-benzimidazol-2-ylamino)methyl]naphthalen-2-ol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 330836-35-6 Structure
  • Basic information

    1. Product Name: 1-[(1H-benzimidazol-2-ylamino)methyl]naphthalen-2-ol
    2. Synonyms: 1-[(1H-Benzimidazol-2-ylamino)methyl]-2-naphthol; 2-Naphthalenol, 1-[(1H-benzimidazol-2-ylamino)methyl]-
    3. CAS NO:330836-35-6
    4. Molecular Formula: C18H15N3O
    5. Molecular Weight: 289.3312
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 330836-35-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 578.1°C at 760 mmHg
    3. Flash Point: 303.4°C
    4. Appearance: N/A
    5. Density: 1.392g/cm3
    6. Vapor Pressure: 5.8E-14mmHg at 25°C
    7. Refractive Index: 1.819
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 1-[(1H-benzimidazol-2-ylamino)methyl]naphthalen-2-ol(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-[(1H-benzimidazol-2-ylamino)methyl]naphthalen-2-ol(330836-35-6)
    12. EPA Substance Registry System: 1-[(1H-benzimidazol-2-ylamino)methyl]naphthalen-2-ol(330836-35-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 330836-35-6(Hazardous Substances Data)

330836-35-6 Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule of the compound.

Explanation

The compound is derived from naphthalenol, which is a type of aromatic compound, and has a benzimidazole group attached to it.
3. Potential antitumor agent

Explanation

Studies have shown that this compound has the potential to be used as an antitumor agent, which means it could be used to treat cancer.
4. Cytotoxic effects on cancer cells

Explanation

The compound has been shown to have cytotoxic effects on cancer cells, meaning it can kill or inhibit the growth of these cells.
5. Minimal toxicity to normal cells

Explanation

The compound has a lower level of toxicity to normal, healthy cells compared to its effects on cancer cells, which is a desirable property for a potential antitumor agent.
6. Inhibitor of tubulin polymerization

Explanation

The compound acts as an inhibitor of tubulin polymerization, a process that is often targeted in the development of anticancer drugs. By inhibiting this process, the compound can disrupt the formation of microtubules, which are essential for cell division and growth.
7. Promising candidate for further research and development

Explanation

Due to its chemical structure, cytotoxic effects, and minimal toxicity to normal cells, this compound is considered a promising candidate for further research and development as a potential treatment for cancer and other related diseases.

Chemical structure

Naphthalenol derivative with a benzimidazole moiety

Check Digit Verification of cas no

The CAS Registry Mumber 330836-35-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,0,8,3 and 6 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 330836-35:
(8*3)+(7*3)+(6*0)+(5*8)+(4*3)+(3*6)+(2*3)+(1*5)=126
126 % 10 = 6
So 330836-35-6 is a valid CAS Registry Number.

330836-35-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(1H-benzimidazol-2-ylamino)methyl]naphthalen-2-ol

1.2 Other means of identification

Product number -
Other names GNF-Pf-2551

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:330836-35-6 SDS

330836-35-6Upstream product

330836-35-6Downstream Products

330836-35-6Relevant articles and documents

Charge-assisted complexation of anions of different dimensionality by benzimidazole-based receptors bearing -OH functionality

Gogoi, Abhijit,Das, Gopal

experimental part, p. 4012 - 4021 (2012/10/18)

Two benzimidazole-based receptors (L1 and L2) bearing -OH functionality form crystalline salts with different organic and inorganic acids viz. [L1H+][Cl-] (1), [L 1H+][NO3-] (2), [L1H +][OAc-] (3), [L1H+][DNB -]DMF (4), [L1H+][H2PO 4-] (5), [L2H+][OAc-]AcOH (6), [L2H+][DNB-] (7), and [L 2H+][HSO4-]H2O (8) where the shape of the counteranion drives the solid structure from a one-dimensional polymeric chain to a three-dimensional structure. Structural analyses show that the anion binding in all eight complexes is attributable entirely to NH +anion, NHanion, OHanion, and multiple CHanion hydrogen bonding interactions. In the solid structure the planar nitrate anion forms a cyclic structure with receptor L1, whereas the acetate anion with the same receptor leads to a molecular barrel type structure. Again the tetrahedral dihydrogen phosphate anion forms a polymeric interanionic chain structure with L1, and the other tetrahedral hydrogen sulfate anion forms hydrogen sulfate-(water)2-hydrogen sulfate adducts with charged L2.

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