331240-24-5Relevant articles and documents
Regioselective C-H Amidation of (Alkyl)arenes by Iron(II) Catalysis
Ding, Yao,Zhang, Shen-Yuan,Chen, Yu-Chen,Fan, Shuai-Xin,Tian, Jie-Sheng,Loh, Teck-Peng
, p. 2736 - 2739 (2019/04/16)
A nondirected amidation reaction of aromatic C-H bond was developed under iron(II) catalysis, using sulfonyl azides as the nitrogen source. The reaction displayed a broad substrate scope and good regioselectivities in the aspects of aromatic ring vs alkyl
INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS
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Paragraph 0063-0064, (2019/01/04)
The present invention concerns a compound having the following formula (I): wherein: - A is in particular -N(R'a)-C(=O)-R, R'a being H or a (C1-C6)alkyl group, and R being preferably a group having the following formula (II): - X is in particular chosen from the group consisting of: -SO2-N(R'b)-, R'b being H or a (C1-C6)alkyl group, -N(R"b)-SO2-, R"b being H or a (C1-C6)alkyl group, -CO-NH-, and -NH-CO-, for use for the treatment of cancers, such as metastatic cancers.
INHIBITORS OF RAC1 AND USES THEREOF FOR INDUCING BRONCHODILATATION
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Paragraph 0064; 0065, (2019/01/04)
The present invention concerns a compound having the following formula (I): wherein: - A is in particular -N(R'a)-C(=O)-R, R'a being H or a (C1-C6)alkyl group, and R being preferably a group having the following formula (II): - X is in particular chosen from the group consisting of: -SO2-N(R'b)-, R'b being H or a (C1-C6)alkyl group, -N(R"b)-SO2-, R"b being H or a (C1-C6)alkyl group, -CO-NH-, and -NH-CO-, for use for the treatment of pathologies characterized by bronchoconstriction, such as asthma.
