- Pyrrolidine modulators of chemokine receptor activity
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The present invention is directed to pyrrolidine compounds of the formula I: (wherein R1, R2, R3, R4, R5, R6, R14and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.
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- Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
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Substituted 2-aminopyridine compounds of Formula (I) and pharmaceutically acceptable salts which have been found useful in the treatment of nitric oxide synthase mediated diseases and disorders. STR1
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- Metal chelating ligands
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Alkyl substitution at the pyridyl periphery of 1, 3, 5, 7-tetra (2-pyridylimino)-benzodipyrroles provides bis chelating ligands with unexpected increase in organic solubility. The bis-chelating ligands may be used to form organometallic polymers as well as being suitable as dyes and metal ion deactivators. The metal complexes of such bis-chelating ligands may also be used as dyes.
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