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5-Methoxy-2-chloropyrazine, a chlorinated pyrazine derivative with the chemical formula C5H5ClN2O, is a yellow liquid compound that features a methoxy group. It serves as a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals, and is also a building block for the preparation of various heterocyclic compounds. Its potential biological and pharmacological activities have made it a valuable target for drug discovery and development.

33332-31-9

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33332-31-9 Usage

Uses

Used in Pharmaceutical Industry:
5-Methoxy-2-chloropyrazine is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique structure allows for the creation of diverse compounds with potential medicinal properties.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Methoxy-2-chloropyrazine is utilized as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its presence in these compounds can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and quality.
Used in Organic Synthesis:
5-Methoxy-2-chloropyrazine is employed as a building block in organic synthesis, enabling the preparation of a wide range of heterocyclic compounds. These compounds have various applications in different fields, including pharmaceuticals, materials science, and chemical research.
Used in Drug Discovery and Development:
Due to its potential biological and pharmacological activities, 5-Methoxy-2-chloropyrazine is used as a target in drug discovery and development. Researchers explore its properties to identify new therapeutic agents and improve existing treatments for various diseases and conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 33332-31-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,3,3 and 2 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 33332-31:
(7*3)+(6*3)+(5*3)+(4*3)+(3*2)+(2*3)+(1*1)=79
79 % 10 = 9
So 33332-31-9 is a valid CAS Registry Number.
InChI:InChI=1S/C5H5ClN2O/c1-9-5-3-7-4(6)2-8-5/h2-3H,1H3

33332-31-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-5-methoxypyrazine

1.2 Other means of identification

Product number -
Other names 2-chloranyl-5-methoxy-pyrazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:33332-31-9 SDS

33332-31-9Upstream product

33332-31-9Downstream Products

33332-31-9Relevant articles and documents

Studies on Pyrazines. 29. High Regioselective Synthesis of Chloropyrazines from 3-Substituted Pyrazine 1-Oxides

Sato, Nobuhiro,Fujii, Megumi

, p. 1177 - 1180 (2007/10/02)

Reaction of 3-methoxy- or 3-chloropyrazine 1-oxides with refluxing phosphoryl chloride in the presence of amine led to a high regioselective formation of 3-substituted 2-chloropyrazines.In contrast, the use of chloroacetyl chloride instead of phosphoryl chloride enabled different regioselectivity to yield 6-substituted 2-chloropyrazines, particularly 3-methoxycarbonylpyrazine 1-oxide was almost exclusively converted into methyl 6-chloropyrazinecarboxylate under conditions without the amine.

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