334974-04-8 Usage
Uses
Used in Chemical Research:
1,2-Dihydroxybenzene-13C is used as a research compound for studying the properties and behavior of molecules in chemical reactions. The presence of the carbon-13 isotope allows for the tracking of specific chemical pathways and the identification of reaction intermediates, providing valuable insights into the underlying mechanisms of various chemical processes.
Used in Biochemical Studies:
In the field of biochemistry, 1,2-Dihydroxybenzene-13C is employed as a labeled compound to investigate the metabolic pathways and enzyme interactions within living organisms. The carbon-13 isotope can be used to trace the incorporation of the compound into biomolecules, enabling researchers to better understand the complex interactions and transformations that occur within biological systems.
Used in Pharmaceutical Development:
1,2-Dihydroxybenzene-13C is also utilized in the development of new pharmaceuticals and drug candidates. The isotopically labeled compound can be used to study the pharmacokinetics and pharmacodynamics of potential drugs, helping to optimize their efficacy and safety profiles. Additionally, it can be employed in the synthesis of novel drug molecules, allowing for the incorporation of the carbon-13 isotope for further research and development purposes.
Used in Environmental Science:
In environmental science, 1,2-Dihydroxybenzene-13C is used as a labeled compound to study the fate and transport of pollutants in the environment. The carbon-13 isotope can be used to track the movement and transformation of contaminants in various environmental matrices, such as soil, water, and air, providing valuable information for the assessment and management of environmental risks.
Used in Analytical Chemistry:
1,2-Dihydroxybenzene-13C is employed as a reference material in analytical chemistry for the calibration of mass spectrometers and other analytical instruments. The presence of the carbon-13 isotope allows for the accurate determination of the compound's molecular weight and the identification of its characteristic isotopic signature, ensuring the reliability and precision of analytical measurements.
Check Digit Verification of cas no
The CAS Registry Mumber 334974-04-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,4,9,7 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 334974-04:
(8*3)+(7*3)+(6*4)+(5*9)+(4*7)+(3*4)+(2*0)+(1*4)=158
158 % 10 = 8
So 334974-04-8 is a valid CAS Registry Number.
334974-04-8Relevant articles and documents
Synthesis of [13C6]-labelled phenethylamine derivatives for drug quantification in biological samples
Karlsen, Morten,Liu, Huiling,Berg, Thomas,Johansen, Jon Eigill,Hoff, Bard Helge
, p. 378 - 387 (2014/06/10)
The availability of high-quality 13C-labelled internal standards will improve accurate quantification of narcotics and drugs in biological samples. Thus, the synthesis of 10 [13C6]-labelled phenethylamine derivatives, namely amphetamine, methamphetamine, 3,4-methylenedioxyamphetamine, 3,4-methylenedioxymethamphetamine, 3,4-methylenedioxy-N-ethylamphetamine, 4-methoxyamphetamine, 4-methoxymethamphetamine, 3,5-dimethoxyphenethylamine 4-bromo-2,5- dimethoxyphenethylamine and 2,5-dimethoxy-4-iodophenethylamine, have been undertaken. [13C6]-Phenol proved to be an excellent starting material for making 13C-labelled narcotic substances in the phenethylamine class, and a developed Stille-type coupling enabled an efficient synthesis of the 3,4-methylenedioxy and 4-methoxy derivatives. The pros and cons of alternative routes and transformations are also discussed. The [ 13C6]-labelled compounds are intended for use as internal standards in forensic analysis, health sciences and metabolomics studies by gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry. Copyright
Synthesis of 13C- and 14C-labelled catechol
Ji, Rong,Schaeffer, Andreas
, p. 551 - 558 (2007/10/03)
13C- and 14C-uniformly labelled catechol was synthesized from phenol in three steps. Phenol was derivatized with 2-chloro-5-nitrobenzophenone in THF containing NaH, followed by ortho-hydroxylation with 35% aqueous H2O
