335204-06-3

Basic information

• Product Name: N-(4-chlorophenyl)-2-phenoxypropanamide
• Synonyms: N-(4-chlorophenyl)-2-phenoxypropanamide
• CAS NO: 335204-06-3
• Molecular Formula: C₁₅H₁₄ClNO₂
• Molecular Weight: 275.73016
• Mol File: 335204-06-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-chlorophenyl)-2-phenoxypropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chlorophenyl)-2-phenoxypropanamide(335204-06-3)
• EPA Substance Registry System: N-(4-chlorophenyl)-2-phenoxypropanamide(335204-06-3)

Safety Data

• Hazardous Substances Data: 335204-06-3(Hazardous Substances Data)

Upstream product

• 940-31-8 2-phenoxypropionic acid 
• 106-47-8 4-chloro-aniline 

Relevant articles and documents

CAL-B-mediated efficient synthesis of a set of valuable amides by direct amidation of phenoxy- and aryl-propionic acids

An efficient, easy and sustainable amidation of a set of non-activated carboxylic acids with anilines, assisted by CAL-B, as biodegradable catalyst, is reported. The enzymatic amidation reactions are performed on set of nonsteroidal anti-inflammatory drugs (NSAIDs), phenoxypropionic acid and protected-prolines by direct condensation of one equivalent of carboxylic acids and two equivalents of anilines derivatives in heptane after 72?h of reaction at 80?°C. The obtained carboxylic amides are recovered with isolated chemical yields varied between moderate and excellent. Fourteen from them are reported for the first time, and an X-ray crystal is obtained for: N-(4-iodophenyl)-2-(4-isobutylphenyl)propanamide 1d.