335419-23-3Relevant articles and documents
Synthesis and in vitro microbiological evaluation of novel 4-aryl-5-isopropoxycarbonyl-6-methyl-3,4-dihydropyrimidinones
Chitra,Devanathan,Pandiarajan
experimental part, p. 367 - 371 (2010/04/04)
Seven 4-aryl-5-isopropoxycarbonyl-6-methyl-3,4-dihydropyrimidin-2(1H)-ones 4a-g and 4-phenyl-5-isopropoxycarbonyl-6-methyl-3,4-dihydropyrimidin-2(1H)-thione 4h have been synthesized by a one-pot cyclocondensation of aldehydes, isopropyl acetoacetate and u
Calcium fluoride: an efficient and reusable catalyst for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones and their corresponding 2(1H)thione: an improved high yielding protocol for the Biginelli reaction
Chitra,Pandiarajan
experimental part, p. 2222 - 2224 (2009/08/07)
A simple and effective synthesis of 3,4-dihydropyrimidinone derivatives from aldehydes, 1,3-dicarbonyl compounds, and urea/thiourea in ethanol by using calcium fluoride as catalyst has been described. Compared with classical Biginelli reaction conditions,
Parallel synthesis of dihydropyrimidinones using Yb(III)-resin and polymer-supported scavengers under solvent-free conditions. A green chemistry approach to the Biginelli reaction
Dondoni, Alessandro,Massi, Alessandro
, p. 7975 - 7978 (2007/10/03)
An efficient synthesis of an array of 3,4-dihydropyrimidin-2-(1H)-ones using solid-supported ytterbium(III) reagent from aldehydes, 1,3-dicarbonyl compounds and urea (Biginelli reaction) under solvent-free conditions is described. Purification of each member of the library was carried out using a cocktail of acid and basic polymer-supported scavengers