Selective reduction of N-protected-α-amino lactones to lactols with lithium tri-tert-butoxyaluminohydride
α-Amino lactols 3 can be prepared in good yield and high optical purity by reduction of α-amino lactones 2 with lithium tri-tert-butoxyaluminohydride (LiAlH(O-t-Bu)3).
Liu, Lee Tai,Huang, Hsiang-Ling,Wang, Chia-Lin Jeff
p. 1329 - 1330
(2007/10/03)
An enantioselective synthesis of (1S,2S)-pseudoephedrine
Synthesis of (1S,2S)-pseudoephedrine is described via reduction of an alanine-derived oxazolidinone followed by treating with phenyl magnesium bromide and chemoselective N-methylation in an efficient and practical manner. (C) 2000 Elsevier Science Ltd.
Vidyasagar Reddy,Venkat Rao,Sreevani,Iyengar
p. 953 - 954
(2007/10/03)
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