cas 33575-81-4, 2-(CHLOROMETHYL)-5-(3,4-DICHLOROPHENYL)-1,3,4-OXADIAZOLE | Articles data ｜lookchem

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33575-81-4

Articles about 33575-81-4Total 3 be found

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COMPOUNDS
A compound for use in the treatment of a disease ameliorated by the inhibition of Notum of formula (I): (I)
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Page/Page column 102

(2020/03/23)

NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE
There is provided compounds of formula (I), or pharmaceutically-acceptable salts thereof, wherein R1 to R4 and X1 to X5 have meanings provided in the description, which compounds are useful in the treatment of c
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Page/Page column 51; 52; 56

(2019/02/13)

AZOLE DERIVATIVES AS WTN PATHWAY INHIBITORS
The present invention relates to new compounds of formula I, to processes for their preparation, to pharmaceutical formulations containing such compounds and to their use in therapy. Such compounds find particular use in the treatment and/or prevention of conditions or diseases which are affected by over-activation of signaling in the Wnt pathway. For example, these may be used in preventing and/or retarding proliferation of tumor cells, for example carcinomas such as colon carcinomas.
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Page/Page column 100-101

(2010/12/29)

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Chemical Properties

Melting Point: 120-122°
Boiling Point: 382.6°Cat760mmHg
Flash Point:185.2°C
Density: 1.5g/cm³
Storage Temp.:2-8°C
Vapor Pressure: 1.03E-05mmHg at 25°C
PSA: 38.92000
LogP: 3.78220

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