336181-28-3Relevant articles and documents
Synthesis and antifungal activity of novel sulfoxide derivatives containing trimethoxyphenyl substituted 1,3,4-thiadiazole and 1,3,4-oxadiazole moiety
Liu, Fang,Luo, Xiao-Qiong,Song, Bao-An,Bhadury, Pinaki S.,Yang, Song,Jin, Lin-Hong,Xue, Wei,Hu, De-Yu
, p. 3632 - 3640 (2008/09/21)
Selective oxidation of sulfides 7 or 8 to sulfoxides 9 or 10 is achieved by mCPBA. The structures of the compounds 9 or 10 are confirmed by elemental analysis, IR, and 1H NMR. The bioassay results showed that title compound 10a possess high ant
Synthesis and antifungal activities of 5-(3,4,5-trimethoxyphenyl)-2-sulfonyl-1,3,4-thiadiazole and 5-(3,4,5-trimethoxyphenyl)-2-sulfonyl-1,3,4-oxadiazole derivatives
Chen, Cai-Jun,Song, Bao-An,Yang, Song,Xu, Guang-Fang,Bhadury, Pinaki S.,Jin, Lin-Hong,Hu, De-Yu,Li, Qian-Zhu,Liu, Fang,Xue, Wei,Lu, Ping,Chen, Zhuo
, p. 3981 - 3989 (2008/02/13)
Starting from the key intermediate 5-(3,4,5-trimethoxyphenyl)-1,3,4-thiadiazole-2-thiol (4) or the oxadiazole analogue (5), the title compounds 9 and 10 are synthesized by a two-step process. Thioetherification reaction of 4 or 5 with an organic halide ca