338454-45-8

Basic information

• Product Name: 5-Hydroxymethylthiophene-2-boronic acid
• Synonyms: 5-HYDROXYMETHYLTHIOPHENE-2-BORONIC ACID;[5-(hydroxyMethyl)thiophen-2-yl]boronic acid;5-(hydroxymethyl)thiophen-2-yl-2-boronic acid;5-Hydroxymethylthiophene-2-boronic acid, >=98%;5-(Hydroxymethyl)thiophene-2-boronic aicd
• CAS NO: 338454-45-8
• Molecular Formula: C₅H₇BO₃S
• Molecular Weight: 157.98
• Product Categories: Boronic Acid
• Mol File: 338454-45-8.mol

Chemical Properties

• Boiling Point: 399.9 °C at 760 mmHg
• Flash Point: 195.6 °C
• Appearance: /
• Density: 1.42 g/cm³
• Vapor Pressure: 4.12E-07mmHg at 25°C
• Refractive Index: 1.594
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 8.42±0.53(Predicted)
• CAS DataBase Reference: 5-Hydroxymethylthiophene-2-boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hydroxymethylthiophene-2-boronic acid(338454-45-8)
• EPA Substance Registry System: 5-Hydroxymethylthiophene-2-boronic acid(338454-45-8)

Safety Data

• Hazardous Substances Data: 338454-45-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Chemistry:
5-Hydroxymethylthiophene-2-boronic acid is used as a reagent in palladium-catalyzed cross-coupling reactions for the synthesis of complex molecules. Its application is crucial in the development of new pharmaceutical compounds, as these reactions allow for the creation of a wide range of molecular structures with potential therapeutic properties.
Used in Scientific Research:
In the field of scientific research, 5-Hydroxymethylthiophene-2-boronic acid is employed as a starting material or intermediate in the synthesis of various organic compounds. Its stability and reactivity make it a valuable component in the preparation of molecules with specific chemical properties, which can be further studied or utilized in different applications.
Used in Drug Synthesis:
5-Hydroxymethylthiophene-2-boronic acid is used as a key component in the synthesis of new drug candidates. Its role in cross-coupling reactions enables the creation of novel molecular entities with potential pharmaceutical applications, contributing to the advancement of drug discovery and development.
Used in Material Science:
In material science, 5-Hydroxymethylthiophene-2-boronic acid can be used as a building block for the development of new materials with specific properties. Its chemical reactivity and stability make it a candidate for the synthesis of materials with tailored characteristics, such as improved conductivity, stability, or other desired attributes.
Used in Environmental Applications:
5-Hydroxymethylthiophene-2-boronic acid can be employed in environmental applications, such as the development of new water treatment processes or the synthesis of environmentally friendly materials. Its water solubility and minimal hazard to humans and the environment when handled appropriately make it a suitable candidate for such applications.

InChI:InChI=1/C5H7BO3S/c7-3-4-1-2-5(10-4)6(8)9/h1-2,7-9H,3H2

Upstream product

• 636-72-6 2-thiophenemethanol 

Downstream Products

• 1220972-77-9 4-[5-(hydroxymethyl)thiophen-2-yl]benzaldehyde 
• 1142945-85-4 (5-{2-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}-thiophen-2-yl)-methanol 

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