339571-21-0

Basic information

• Product Name: N-(3-pyridinyl)-1-adamantanecarboxamide
• Synonyms: N-(3-pyridinyl)-1-adamantanecarboxamide;N-(pyridin-3-yl)tricyclo[3.3.1.1~3,7~]decane-1-carboxamide
• CAS NO: 339571-21-0
• Molecular Formula: C16H20N2O
• Molecular Weight: 256.3428
• Mol File: 339571-21-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(3-pyridinyl)-1-adamantanecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-pyridinyl)-1-adamantanecarboxamide(339571-21-0)
• EPA Substance Registry System: N-(3-pyridinyl)-1-adamantanecarboxamide(339571-21-0)

Safety Data

• Hazardous Substances Data: 339571-21-0(Hazardous Substances Data)

Upstream product

• 462-08-8 pyridin-3-ylamine 
• 2094-72-6 1-Adamantanecarbonyl chloride 
• 828-51-3 1-Adamantanecarboxylic acid 

Relevant articles and documents

Construction of a novel INHIBIT logic gate through a fine-tuned assembly of anthryl fluorophores via selective anion recognition and host-guest interactions

A novel ligand (AAP) based on an anthryl fluorophore was rationally designed and synthesized. The presence of H2PO4- (Pi) could induce the effective assembly of the ligand which leads to a strong excimer emission, while β-cyclodextrin (β-CD) disassembled the Pi-ligand complex through a host-guest interaction with terminal adamantane groups. This disassembly causes a considerable decrement in emissive intensity as well as a clear blue-shift in emissive wavelength. By manipulating the assembly and disassembly of anthryl fluorophores with Pi and β-CD, a novel INHIBIT logic gate was constructed using Pi and β-CD as the chemical inputs and fluorescence emission as the output.

11-BETA-HYDROXYSTEROID DEHYDROGENASE INHIBITORS

There is provided a compound having Formula (I ) R1-Z-R2 wherein R1 is a group selected from optionally substituted fused polycyclic groups, substituted alkyl groups, branched alkyl groups, and optionally substituted cycioalkyl groups Z is a linker which is or comprises a carbonyl group or a isostere of a carbonyl group R2 is selected from optionally substituted aromatic rings and optionally substituted heterocyclic rings wherein (a) R2 is a 2-substituted thiophene group, and/or (b) Z is a group of the formula -C(=O)-CR3R4-X-(CR5R6)n-, wherein X is selected from NR7, S, O, S=O, and S(=O)2, wherein n is 0 or 1 and/or (c) R1 is an adamantyl group and Z is or comprises an amide group, and/or (d) R1 is an adamantyl group and Z is or comprises a group of the formula -(CR8R9)p- NR10-S(=O)2-(CR11R12)q-, wherein p is 0 or 1 and q is 0 or 1 and/or (e) R1 is an adamantyl group and Z is or comprises a group of the formula -(CR13R14)V-Y- (CR15R16)W- where Y is a heteroaryl group in which a bond in the heteroaryl ring is a isostere of a carbonyl group, wherein v is o or 1 and w is 0 or 1 ; wherein each of R3, R4, R5, R6, R8, R9, R11, R12, R13, R14, R15 and R16, are independently selected from H, hydrocarbyl and halogen, wherein each of R7 and R10 are independently selected from H and hydrocarbyl.