342600-96-8

Basic information

• Product Name: 2-(5-BroMopyridin-3-yl)oxazole
• Synonyms: 2-(5-BroMopyridin-3-yl)oxazole
• CAS NO: 342600-96-8
• Molecular Formula: C8H5BrN2O
• Molecular Weight: 225.0421
• Mol File: 342600-96-8.mol

Chemical Properties

• Boiling Point: 327.195°C at 760 mmHg
• Flash Point: 151.683°C
• Appearance: /
• Density: 1.606g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.586
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(5-BroMopyridin-3-yl)oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-BroMopyridin-3-yl)oxazole(342600-96-8)
• EPA Substance Registry System: 2-(5-BroMopyridin-3-yl)oxazole(342600-96-8)

Safety Data

• Hazardous Substances Data: 342600-96-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(5-Bromopyridin-3-yl)oxazole serves as a crucial intermediate in organic synthesis, particularly for the development of biologically active molecules. Its unique structure and reactivity make it an essential component in the creation of new pharmaceutical compounds.
Used in Cancer Research and Treatment:
2-(5-Bromopyridin-3-yl)oxazole has demonstrated potential as a novel anti-cancer agent. Studies have shown its ability to inhibit the growth of certain cancer cells, making it a promising candidate for further research and development in oncology. This application highlights its importance in the ongoing quest for new and effective cancer treatments.

InChI:InChI=1/C8H5BrN2O/c9-7-3-6(4-10-5-7)8-11-1-2-12-8/h1-5H

Upstream product

• 342600-95-7 C₁₀H₁₃BrN₂O₂ 
• 113118-81-3 5-bromopyridine-3-carbaldehyde 

Downstream Products

• 1201644-46-3 C₁₄H₁₇BN₂O₃ 

Relevant articles and documents

TRICYCLIC SUBSTITUTED THIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE

In its many embodiments, the present invention provides provides certain iminothiazine dioxide compounds, including compounds Formula (I): (I) and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomero

2-SPIRO-SUBSTITUTED IMINOTHIAZINES AND THEIR MONO-AND DIOXIDES AS BACE INHIBITORS, COMPOSITIONS AND THEIR USE

In its many embodiments, the present invention provides provides certain iminothiazine dioxide compounds, including compounds Formula (I): and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomeros and said stereoisomers, wherein each of the variables shown in the formula are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including Alzheimer's disease, are also disclosed

Gamma-hydroxy-2-(fluoroalkylaminocarbonyl)-1-piperazinepentanamides and uses thereof

γ-Hydroxy-2-(fluoroalkylaminocarbonyl)-1-piperazinepentanamide compounds are inhibitors of HIV protease and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described. These compounds are effective against HIV viral mutants which are resistant to HIV protease inhibitors currently used for treating AIDS and HIV infection.