Discovery and development of a small molecule library with lumazine synthase inhibitory activity
(Chemical Equation Presented) (E)-5-Nitro-6-(2-hydroxystyryl)pyrimidine-2, 4(1H,3H)-dione (9) was identified as a novel inhibitor of Schizosaccharomyces pombe lumazine synthase by high-throughput screening of a 100000 compound library. The Ki o
Talukdar, Arindam,Breen, Meghan,Bacher, Adelbert,Illarionov, Boris,Fischer, Markus,Georg, Gunda,Ye, Qi-Zhuang,Cushman, Mark
experimental part
p. 5123 - 5134
(2009/12/24)
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