343832-73-5

Basic information

• Product Name: METHYL [4,5-DIMETHOXY-2-(MORPHOLINE-4-SULFONYL)-PHENYL]-ACETATE
• Synonyms: METHYL 2-[4,5-DIMETHOXY-2-(MORPHOLINOSULFONYL)PHENYL]ACETATE;METHYL [4,5-DIMETHOXY-2-(MORPHOLINE-4-SULFONYL)-PHENYL]-ACETATE
• CAS NO: 343832-73-5
• Molecular Formula: C₁₅H₂₁NO₇S
• Molecular Weight: 359.39
• Mol File: 343832-73-5.mol

Chemical Properties

• Melting Point: 96-99°C
• Appearance: /
• CAS DataBase Reference: METHYL [4,5-DIMETHOXY-2-(MORPHOLINE-4-SULFONYL)-PHENYL]-ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL [4,5-DIMETHOXY-2-(MORPHOLINE-4-SULFONYL)-PHENYL]-ACETATE(343832-73-5)
• EPA Substance Registry System: METHYL [4,5-DIMETHOXY-2-(MORPHOLINE-4-SULFONYL)-PHENYL]-ACETATE(343832-73-5)

Safety Data

• Hazardous Substances Data: 343832-73-5(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 15964-79-1 methyl (3,4-dimethoxyphenyl)acetate 

Downstream Products

• 63212-44-2 [4,5-dimethoxy-2-(morpholine-4-sulfonyl)-phenyl]-acetic acid 

Relevant articles and documents

Use of receptor chimeras to identify small molecules with high affinity for the dynorphin A binding domain of the κ opioid receptor

A series of 2-substituted sulfamoyl arylacetamides of general structure 2 were prepared as potent κ opioid receptor agonists and the affinities of these compounds for opioid and chimeric receptors were compared with those of dynorphin A. Compounds 2e and 2i were identified as non-peptide small molecules that bound to chimeras 3 and 4 with high affinities similar to dynorphin A, resulting in Ki values of 1.5 and 1.2 nM and 1.3 and 2.2 nM, respectively.