343856-70-2

Basic information

• Product Name: 3-(3-methylphenyl)piperidine(SALTDATA: HCl)
• Synonyms: 3-(3-methylphenyl)piperidine(SALTDATA: HCl)
• CAS NO: 343856-70-2
• Molecular Formula: C₁₂H₁₇N
• Molecular Weight: 175.27008
• Mol File: 343856-70-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(3-methylphenyl)piperidine(SALTDATA: HCl)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-methylphenyl)piperidine(SALTDATA: HCl)(343856-70-2)
• EPA Substance Registry System: 3-(3-methylphenyl)piperidine(SALTDATA: HCl)(343856-70-2)

Safety Data

• Hazardous Substances Data: 343856-70-2(Hazardous Substances Data)

Upstream product

• 28987-79-3 m-tolylmagnesium bromide 
• 626-55-1 3-Bromopyridine 
• 4385-67-5 3-(3-methylphenyl)pyridine 

Downstream Products

• 1402155-51-4 C₂₄H₃₁N₅O 
• 344256-97-9 1-(3-m-Tolyl-piperidin-1-yl)-propan-1-one 

Relevant articles and documents

3-Phenylpiperidines. Central Dopamine-Autoreceptor Stimulating Activity

Thirty compounds related to the selective dopamine-autoreceptor agonist 3-(3-hydroxyphenyl)-N-n-propylpiperidine have been synthesized and tested for central dopamine-autoreceptor stimulating activity.The 3-(3-hydroxyphenyl)piperidine moiety seems indispensable for high potency and selectivity.Introduction of an additional hydroxyl group into the 4-position of the aromatic ring gives a compound with dopaminergic activity but lacking selectivity for autoreceptors. 3-(3-Hydroxyphenyl)-N-n-propylpyrrolidine, 3-(3-hydroxy)-N-n-propylperhydroazepine, and 3-(3-hydroxyphenyl)quinuclidine were all inactive.The most potent compounds were the N-isopropyl-, N-n-butyl-, N-n-pentyl-, and N-phenethyl-substituted 3-(3-hydroxyphenyl)piperidine derivatives.None of the compounds investigated seemed to have central noradrenaline- or serotonin-receptor stimulating activity.