cas 345-78-8, (1S,2S)-(+)-Pseudoephedrine hydrochloride

Articles about 345-78-8Total 4 be found

An efficient synthesis of aziridines from ephedrines
The reaction of chlorodeoxyephedrine hydrochlorides with one, two, and three molar equivalents of base was studied. Isochlorodeoxypseudoepherines were identified and assigned by 1H and 13C NMR data as intermediate compounds in the formation of cis-aziridines. Erythro and threo ephedrinethylethers were isolated as new compounds and analyzed by spectroscopic data. In addition, the erythro isomer was studied by X-ray diffraction.
Cruz, Alejandro,Padilla-Martinez, Itzia Irene,Garcia-Baez, Efren V.
scheme or table
p. 909 - 913
(2010/08/19)

Popping oral pharmaceutical compositions
Disclosed are popping pharmaceutical compositions, which comprise OTC or prescription drug, and popping material. The popping material includes pressurized gas trapped within cavities of a pharmaceutically acceptable material in a manner that allows the gas to escape from the pharmaceutical composition upon dissolution, contact with saliva or shattering of the popping material. Such an oral pharmaceutical composition may be popular with children that will prefer it on other ones, which do not pop. Methods for preparation of such oral pharmaceutical compositions are also disclosed.
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(2008/06/13)

An enantioselective synthesis of (1S,2S)-pseudoephedrine
Synthesis of (1S,2S)-pseudoephedrine is described via reduction of an alanine-derived oxazolidinone followed by treating with phenyl magnesium bromide and chemoselective N-methylation in an efficient and practical manner. (C) 2000 Elsevier Science Ltd.
Vidyasagar Reddy,Venkat Rao,Sreevani,Iyengar
p. 953 - 954
(2007/10/03)

Ueber die Stereoselektivitaet der 9,9'-Spirobifluoren-kronenaether gegenueber α-Aminoalkoholen
Crown ethers I-VI were tested by partition experiments for their stereoselectivity towards α-amino alcohols 1-10.The stereoselectivity depends in a regular way on both the absolute and relative configuration of the crown ether and α-amino alcohol.Comments are made on some high stereoselectivities.
Prelog, Vladimir,Mutak, Stjepan
p. 2274 - 2278
(2007/10/02)

Chemical Properties

Appearance/Colour :white powder
Melting Point: 185-188 °C(lit.)
Boiling Point: 255 °C at 760 mmHg
Flash Point:85.6 °C
Solubility:Freely soluble in water and in ethanol (96 per cent), sparingly soluble in methylene chloride.
Storage Temp.:Refrigerator (+4°C)
Vapor Pressure: 0.00865mmHg at 25°C
PKA: 9.22(at 25℃)
Merck: 13,8007
BRN: 3915112
PSA: 32.26000
LogP: 2.52080

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