345912-39-2

Basic information

• Product Name: 3-amino-N-(4-methylphenyl)-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide
• Synonyms: 3-amino-N-(4-methylphenyl)-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide
• CAS NO: 345912-39-2
• Molecular Formula: C₂₄H₂₁N₃OS
• Molecular Weight: 399.50804
• Mol File: 345912-39-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-amino-N-(4-methylphenyl)-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-amino-N-(4-methylphenyl)-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide(345912-39-2)
• EPA Substance Registry System: 3-amino-N-(4-methylphenyl)-4-phenyl-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide(345912-39-2)

Safety Data

• Hazardous Substances Data: 345912-39-2(Hazardous Substances Data)

Upstream product

• 345912-27-8 2-(3-cyano-4-phenyl-6,7-dihydro-5H-[1]pyrindin-2-ylsulfanyl)-N-p-tolyl-acetamide 
• 83236-48-0 4-phenyl-2-thioxo-2,5,6,7-tetrahydro-1H-cyclopenta[b]pyridine-3-carbonitrile 
• 16634-82-5 N-(p-tolyl)-2-chloroacetamide 

Relevant articles and documents

Synthesis of some new thieno[2,3-b]pyridines, pyrido[3′,2′:4,5]-thieno[3,2-d]pyrimidines and pyrido[3′,2′:4,5]thieno[3,2-d][1,2,3]-triazines

4-Aryl-3-cyano-2-substituted-methylthiocyclopenta[b]pyridines (3a-c and 4a-i) were prepared by reaction of 4-aryl-3-cyanocyclopenta[b]pyridine-2(1H)-thiones(2a-c) with chloroacetonitrile or chloro-N-arylacelamides, respectively. On treatment of these products with sodium ethoxide in boiling ethanol, they underwent intramolecular Thorpe-Ziegler cyclization to afford the corresponding 3-amino-4-aryl-2-functionallized-cyclopenta[e]thieno [2,3-b]pyridines (5a-c and 6a-i). Most of the latter thienopyridines were used as synthons for the target cyclopenta[5′,6′]pyrido[3′,2′:4,5]thieno[3,2-d] pyrimidines and cyclopenta[5′,6′] pyrido[3′,2′:4,5]thieno[3,2-d)[1,2,3]triazines.