345953-41-5 Usage
Uses
Used in Organic Synthesis:
(2-bromo-4-(bromomethyl)phenyl)methanol is used as a building block in organic synthesis for the creation of various chemical compounds. Its unique structure and reactivity allow for the development of new molecules with specific properties and functions.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (2-bromo-4-(bromomethyl)phenyl)methanol is utilized as a key intermediate in the synthesis of drugs. Its presence of bromine atoms can be leveraged to form new medicinal compounds with potential therapeutic effects.
Used in Chemical Research and Development:
Due to its structural versatility and reactivity, (2-bromo-4-(bromomethyl)phenyl)methanol is employed in chemical research and development to explore new chemical reactions and investigate its potential applications in various fields.
It is important to handle (2-bromo-4-(bromomethyl)phenyl)methanol with care, as brominated chemicals can be hazardous if not properly managed.
Check Digit Verification of cas no
The CAS Registry Mumber 345953-41-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,5,9,5 and 3 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 345953-41:
(8*3)+(7*4)+(6*5)+(5*9)+(4*5)+(3*3)+(2*4)+(1*1)=165
165 % 10 = 5
So 345953-41-5 is a valid CAS Registry Number.
345953-41-5Relevant articles and documents
The development of potent non-peptidic PTP-1B inhibitors
Dufresne, Claude,Roy, Patrick,Wang, Zhaoyin,Asante-Appiah, Ernest,Cromlish, Wanda,Boie, Yves,Forghani, Farnaz,Desmarais, Sylvie,Wang, Qingping,Skorey, Kathryn,Waddleton, Deena,Ramachandran, Chidambaram,Kennedy, Brian P.,Xu, Lijing,Gordon, Robert,Chan, Chi Chung,Leblanc, Yves
, p. 1039 - 1042 (2007/10/03)
The SAR from our peptide libraries was exploited to design a series of potent deoxybenzoin PTP-1B inhibitors. The introduction of an ortho bromo substituent next to the difluoromethylphosphonate warhead gave up to 20-fold increase in potency compared to the desbromo analogues. In addition, these compounds were orally bioavailable and active in the animal models of non-insulin dependent diabetes mellitus (NIDDM).
