349451-44-1

Basic information

• Product Name: (R)-N-(5-nitropyrid-2-yl)-2-hydroxy-1-phenylethylamine
• Synonyms: (R)-N-(5-nitropyrid-2-yl)-2-hydroxy-1-phenylethylamine
• CAS NO: 349451-44-1
• Molecular Formula: C₁₃H₁₃N₃O₃
• Molecular Weight: 259
• Mol File: 349451-44-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-N-(5-nitropyrid-2-yl)-2-hydroxy-1-phenylethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-(5-nitropyrid-2-yl)-2-hydroxy-1-phenylethylamine(349451-44-1)
• EPA Substance Registry System: (R)-N-(5-nitropyrid-2-yl)-2-hydroxy-1-phenylethylamine(349451-44-1)

Safety Data

• Hazardous Substances Data: 349451-44-1(Hazardous Substances Data)

Upstream product

• 4548-45-2 2-chloro-5-nitropyridine 
• 56613-80-0 D-2-phenylglycinol 

Relevant articles and documents

Enantioselective acyl transfer catalysts and their use in kinetic resolution of alcohols and desymmetrization of meso-diols

Novel enantioselective acylation catalysts comprising chiral derivatives of DHIP and DHIQ, having the following representative general structures are disclosed: These new compounds are useful for resolving racemates or further enhancing the enantiomeric excess of an enantiomerically enriched composition and for desymmetrizing meso compounds.

2,3-Dihydroimidazo[1,2-a]pyridines: A new class of enantioselective acyl transfer catalysts and their use in kinetic resolution of alcohols

The long-known, but previously unexplored 2,3-dihydroimidazo[1,2-a]pyridine (DHIP) has been shown to be a competent acyl transfer catalyst. Its chiral 2-phenyl derivatives obtainable in two steps from commercially available starting materials have proved to be effective acylation catalysts, giving high levels of enantioselectivity (s = 20-85) in kinetic resolution of secondary benzylic alcohols. A transition state model explaining the observed selectivity has been proposed. Copyright