350847-80-2

Basic information

• Product Name: 5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)
• Synonyms: 5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI);6,7-Dihydro-5H-[2]pyrindin-5-one;6,7-dihydro-5H-cyclopenta[c]pyridin-5-one;6,7-Dihydro-5H-cyclopental[c]pyridine-5-one;6,7-dihydrocyclopenta[c]pyridin-5-one;6,7-Dihydro-5H-cyclopental[c]pyridin-5-one;5H,6H,7H-cyclopenta[c]pyridin-5-one;5H-Cyclopenta[c]pyridin-5-one, 6,7-dihydro-
• CAS NO: 350847-80-2
• Molecular Formula: C₈H₇NO
• Molecular Weight: 133.149
• Product Categories: PYRIDINE
• Mol File: 350847-80-2.mol

Chemical Properties

• Boiling Point: 267.379 °C at 760 mmHg
• Flash Point: 122.62 °C
• Appearance: /
• Density: 1.23 g/cm³
• Vapor Pressure: 0.008mmHg at 25°C
• Refractive Index: 1.592
• PKA: 3.56±0.20(Predicted)
• CAS DataBase Reference: 5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)(350847-80-2)
• EPA Substance Registry System: 5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)(350847-80-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 350847-80-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its potential anti-inflammatory and anti-cancer properties. Its unique structure allows for the development of new drugs with improved efficacy and reduced side effects.
Used in Organic Synthesis:
In the field of organic synthesis, 5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI) serves as a versatile building block for the preparation of a wide range of biologically active compounds. Its reactivity and structural features enable the creation of diverse molecules with potential applications in various industries.
Used in Agrochemical Development:
5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI) is also utilized in the development of new agrochemicals, where its unique properties can contribute to the creation of more effective and environmentally friendly products for agricultural applications.
Used in Research and Development:
Due to its potential anti-inflammatory and anti-cancer properties, 5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI) is extensively used in research and development for the discovery of novel therapeutic agents and the advancement of drug design strategies.

InChI:InChI=1/C8H7NO/c10-8-2-1-6-5-9-4-3-7(6)8/h3-5H,1-2H2

Upstream product

• 350847-73-3 3-oxazol-5-yl-propan-1-ol 
• 59786-31-1 methyl 3-bromoisonicotinate 
• 19608-41-4 methyl 3-(3-ethoxy-3-oxopropyl)isonicotinate 
• 350847-76-6 5-oxazol-5-yl-pent-1-en-3-ol 
• 143184-88-7 3-oxazol-5-yl-propionaldehyde 
• 350847-78-8 5-oxazol-5-yl-pent-1-en-3-one 

Relevant articles and documents

Effect of copper(II) triflate on intramolecular Diels-Alder reaction of oxazole-olefins

Intramolecular Diels - Alder reaction of the oxazole-olefins (8a) and (11a) was effectively promoted by addition of a catalytic amount of copper(II) triflate to afford the cyclopenta[c]pyridines (9a) and (12a), respectively.

PLASMA KALLIKREIN INHIBITORS AND USES THEREOF

The present invention provides compounds and compositions thereof which are useful as inhibitors of plasma kallikrein and which exhibit desirable characteristics for the same.

DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS

Compounds of formula I: I are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disorders in a patient in need are also disclosed. Such disorders include depression, bipolar disorder, pain, schizophrenia, obsessive compulsive disorder, addiction, social disorder, attention deficit hyperactivity disorder, an anxiety disorder, autism, a cognitive impairment, or a neuropsychiatric symptom such as apathy, depression, anxiety, psychosis, aggression, agitation, impulse control disorders, and sleep disorders in neurological disorders such as Alzheimer's and Parkinson's diseases.