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351325-41-2

7H-1,3-Dioxolo[4,5-f]indol-7-one, 6-ethyl-, 5-oxide (9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 351325-41-2 Structure

  • Basic information

    1. Product Name: 7H-1,3-Dioxolo[4,5-f]indol-7-one, 6-ethyl-, 5-oxide (9CI)
    2. Synonyms: 7H-1,3-Dioxolo[4,5-f]indol-7-one, 6-ethyl-, 5-oxide (9CI)
    3. CAS NO:351325-41-2
    4. Molecular Formula: C11H9NO4
    5. Molecular Weight: 219.19346
    6. EINECS: N/A
    7. Product Categories: ALCOHOL
    8. Mol File: 351325-41-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 7H-1,3-Dioxolo[4,5-f]indol-7-one, 6-ethyl-, 5-oxide (9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 7H-1,3-Dioxolo[4,5-f]indol-7-one, 6-ethyl-, 5-oxide (9CI)(351325-41-2)
    11. EPA Substance Registry System: 7H-1,3-Dioxolo[4,5-f]indol-7-one, 6-ethyl-, 5-oxide (9CI)(351325-41-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 351325-41-2(Hazardous Substances Data)

351325-41-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 351325-41-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,1,3,2 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 351325-41:
(8*3)+(7*5)+(6*1)+(5*3)+(4*2)+(3*5)+(2*4)+(1*1)=112
112 % 10 = 2
So 351325-41-2 is a valid CAS Registry Number.

351325-41-2Downstream Products

351325-41-2Relevant articles and documents

Synthesis and antiplasmodial activity of new indolone N-Oxide derivatives

Nepveu, Fran?oise,Kim, Sothea,Boyer, Jeremie,Chatriant, Olivier,Ibrahim, Hany,Reybier, Karine,Monje, Marie-Carmen,Chevalley, Severine,Perio, Pierre,Lajoie, Barbora H.,Bouajila, Jalloul,Deharo, Eric,Sauvain, Michel,Tahar, Rachida,Basco, Leonardo,Pantaleo, Antonella,Turini, Francesco,Arese, Paolo,Valentin, Alexis,Thompson, Eloise,Vivas, Livia,Petit, Serge,Nallet, Jean-Pierre

experimental part, p. 699 - 714 (2010/07/09)

A series of 66 new indolone-N-oxide derivatives was synthesized with three different methods. Compounds were evaluated for in vitro activity against CQ-sensitive (3D7), CQ-resistant (FcB1), and CQ and pyrimethamine cross-resistant (K1) strains of Plasmodium falciparum (P.f.), aswell as for cytotoxic concentration (CC50) on MCF7 and KB human tumor cell lines. Compound 26 (5-methoxy-indolone-N-oxide analogue) had the most potent antiplasmodial activity in vitro (50 MCF7/IC50 FcB1: 14623; CC50 KB/IC50 3D7: 198823). In in vivo experiments, compound 1 (dioxymethylene derivatives of the indolone-N-oxide) showed the best antiplasmodial activity against Plasmodium berghei, 62% inhibition of the parasitaemia at 30 mg/kg/day. 2009 American Chemical Society.

A new general approach for the synthesis of 2-substituted-3H-indol-3-one N-oxide derivatives

Ge?nisson, Vania Bernardes,Bouniol, Anne-Vale?rie,Nepveu, Franc?oise

, p. 700 - 702 (2007/10/03)

2-aryl (phenyl, 1,3-benzodioxolyl) and 2-alkyl (ethyl, sec-butyl)-3H-indol-3-one N-oxides were synthesized by a new general method involving a reductive intramolecular cyclization reaction of ortho-diketo nitrobenzene derivatives.

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