cas 35158-23-7, 1-(2-HYDROXY-3,5-DIISOPROPYLPHENYL)ETHANONE | Articles data ｜lookchem

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35158-23-7

Articles about 35158-23-7Total 3 be found

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Survivin inhibitors
Compounds that inhibit survivin, compositions containing the compounds and methods of treating diseases in which survivin is unregulated or overexpressed are disclosed.
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Page/Page column 22

(2010/11/26)

SUBSTITUTED FUROCHROMENE COMPOUNDS OF ANTIINFLAMMATORY ACTION
The present invention relates to novel compounds of the formula (I) including all stereoisomers and tautomers, to the pharmaceutically acceptable salts and solvates thereof, to the processes and reactive intermediates for their preparation and to their use in the prophylaxis and treatment of asthma and other inflammatory diseases and/or conditions in humans.
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Page/Page column 69-70

(2010/02/10)

Novel (2E,4E,6Z)-7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta-2,4,6-trienoic acid retinoid X receptor modulators are active in models of type 2 diabetes
Previous data have shown that RXR-selective agonists (e.g., 3 and 4) are insulin sensitizers in rodent models of non-insulin-dependent diabetes mellitus (NIDDM). Unfortunately, they also produce dramatic increases in triglycerides and profound suppression
Michellys,Ardecky,Chen,Crombie,Etgen,Faul,Faulkner,Grese,Heyman,Karanewsky,Klausing,Leibowitz,Liu,Mais,Mapes,Marschke,Reifel-Miller,Ogilvie,Rungta,Thompson,Tyhonas,Boehm
p. 2683 - 2696
(2007/10/03)

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Chemical Properties

Melting Point: 37°C
Boiling Point: 288.5±35.0 °C(Predicted)
Density: 1.003±0.06 g/cm3(Predicted)
PKA: 10.97±0.23(Predicted)
PSA: 37.30000
LogP: 3.84160

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