352330-84-8

Basic information

• Product Name: 2-(2-bromophenyl)-5-methyl-1,3,4-oxadiazole
• CAS NO: 352330-84-8
• Molecular Formula: C₉H₇BrN₂O
• Molecular Weight: 239.0687
• Mol File: 352330-84-8.mol

Chemical Properties

• Boiling Point: 339.713°C at 760 mmHg
• Flash Point: 159.253°C
• Density: 1.528g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: 2-(2-bromophenyl)-5-methyl-1,3,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromophenyl)-5-methyl-1,3,4-oxadiazole(352330-84-8)
• EPA Substance Registry System: 2-(2-bromophenyl)-5-methyl-1,3,4-oxadiazole(352330-84-8)

Safety Data

• Hazardous Substances Data: 352330-84-8(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic compound

Elements present

Carbon (C), Hydrogen (H), Bromine (Br), Nitrogen (N), and Oxygen (O)

Biological and pharmacological activities

Antimicrobial and antioxidant properties

Synthesis applications

Used in the synthesis of other organic compounds and materials

Importance of bromine atom

Valuable for various synthetic applications

Unique structure

Heterocyclic structure makes it a building block for creating new compounds with potential medicinal and industrial applications.

Upstream product

• 79-24-3 Nitroethane 
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Relevant articles and documents

Electrophilic activation of nitroalkanes in efficient synthesis of 1,3,4-oxadiazoles

A novel methodology for general and chemoselective preparation of non-symmetric 1,3,4-oxadiazoles is developed. This unusual reaction proceeds via polyphosphoric acid-assisted activation of nitroalkanes towards nucleophilic attack with acylhydrazides.

Iodine-catalysed oxidative cyclisation of acylhydrazones to 2,5-substituted 1,3,4-oxadiazoles

An environmentally benign synthesis of 2,5-disubstituted 1,3,4-oxadiazoles has been developed starting from N-aroylhydrazones and N-acetylhydrazones at room or ambient temperature using a catalytic quantity of iodine in the presence of an aqueous hydrogen peroxide oxidant.