352356-38-8

Basic information

• Product Name: (1R,2S)-BOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID
• Synonyms: (1R,2S)-BOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID;(1R,2S)-BOC-ACHC;(1R,2S)-2-tert-Butoxycarbonylamino-cyclohexanecarboxylic acid;(1R,2S)-2-(tert-butoxycarbonyl)cyclohexanecarboxylic acid;(1R,2S)-2-((tert-Butoxycarbonyl)amino)cyclohexane-1-carboxylic acid;(1R,2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]cyclohexane-1-carboxylic acid
• CAS NO: 352356-38-8
• Molecular Formula: C₁₂H₂₁NO₄
• Molecular Weight: 243.3
• Mol File: 352356-38-8.mol

Chemical Properties

• Boiling Point: 396.7±31.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.86±0.44(Predicted)
• CAS DataBase Reference: (1R,2S)-BOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S)-BOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID(352356-38-8)
• EPA Substance Registry System: (1R,2S)-BOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID(352356-38-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 352356-38-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(1R,2S)-BOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID is used as a building block in organic synthesis for its ability to participate in a range of chemical reactions, leading to the formation of diverse molecular structures. Its chirality and protecting group make it a versatile intermediate in the creation of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (1R,2S)-BOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID is used as a key intermediate in the synthesis of various bioactive molecules. The BOC protecting group can be selectively removed under mild conditions, revealing the free amino group, which is crucial for the formation of peptides and other pharmaceutically relevant compounds.
Used in Material Science:
(1R,2S)-BOC-2-AMINOCYCLOHEXANE CARBOXYLIC ACID is also utilized in material science for its potential to form novel materials with specific properties. Its reactivity and structural features allow for the development of new polymers, coatings, or other materials with tailored characteristics for various applications.

Upstream product

• 7758-19-2 sodium chlorite 
• 513-35-9 2-methyl-but-2-ene 
• 352356-37-7 tert-butyl [(1S,2R)-2-formylcyclohexyl]carbamate 
• 805994-98-3 ethyl (1R,2S)-2-[(tert-butoxycarbonyl)amino]cyclohexanecarboxylate 

Downstream Products

• 477349-88-5 1-[(1R,2S)-2-(t-butoxycarbonylamino)cyclohexyl]-N-[(2S)-1-[3-cyclopropylmethyl-2-oxo-1,3,4-oxadiazolin-5-yl]-1-hydroxy-4-methyl-2-pentyl]carboxamide 
• 680568-92-7 tert-butyl (1S,2R)-2-{[(cyanomethyl)amino]carbonyl}cyclohexylcarbamate 

Relevant articles and documents

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