35299-87-7

Basic information

• Product Name: 4-hydroxyochratoxin A
• Synonyms: 4-hydroxyochratoxin A;(4S)-4-Hydroxyochratoxin A;N-[[(3R)-1-Oxo-3α-methyl-5-chloro-4β,8-dihydroxyisochroman-7-yl]carbonyl]-L-phenylalanine;N-[[(3R,4S)-4-Hydroxy-5-chloro-3,4-dihydro-8-hydroxy-3α-methyl-1-oxo-1H-2-benzopyran]-7-ylcarbonyl]-L-Phe-OH
• CAS NO: 35299-87-7
• Molecular Formula: C20H18ClNO7
• Molecular Weight: 419.81242
• Mol File: 35299-87-7.mol

Chemical Properties

• Boiling Point: 639.1°Cat760mmHg
• Flash Point: 340.3°C
• Appearance: /
• Density: 1.498g/cm³
• Vapor Pressure: 3.28E-17mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 4-hydroxyochratoxin A(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxyochratoxin A(35299-87-7)
• EPA Substance Registry System: 4-hydroxyochratoxin A(35299-87-7)

Safety Data

• Hazardous Substances Data: 35299-87-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
4-Hydroxyochratoxin A is used as a research compound for understanding the mechanisms of renal carcinogenesis and the effects of genotoxic substances on the kidney. Its role as a renal carcinogen in rats provides valuable insights into the development of kidney cancer and the potential risks associated with exposure to similar compounds in humans.
Used in Toxicology Studies:
As a known metabolite in humans and a potent renal carcinogen, 4-Hydroxyochratoxin A is used in toxicology studies to investigate the potential health risks and safety concerns associated with exposure to this mycotoxin. These studies contribute to the development of guidelines and regulations for safe exposure levels and the prevention of mycotoxin-related health issues.
Used in Environmental Monitoring:
4-Hydroxyochratoxin A is used as a biomarker in environmental monitoring to detect the presence of mycotoxins in food and feed products. Early detection of this compound can help prevent contamination and ensure the safety of the food supply, protecting human and animal health from the potential carcinogenic effects of this mycotoxin.
Used in Agricultural Applications:
In the agricultural industry, 4-Hydroxyochratoxin A is used as a reference compound for the development of strategies to control the growth of mycotoxin-producing fungi in crops. By understanding the conditions that promote the production of this toxin, farmers and researchers can implement effective measures to reduce the risk of mycotoxin contamination in the food supply.

InChI:InChI=1/C20H18ClNO7/c1-9-16(23)14-12(21)8-11(17(24)15(14)20(28)29-9)18(25)22-13(19(26)27)7-10-5-3-2-4-6-10/h2-6,8-9,13,16,23-24H,7H2,1H3,(H,22,25)(H,26,27)/t9-,13+,16+/m1/s1