353281-15-9

Usage

Uses

Used in Chemical Synthesis:
2-Chloro-3-nitro-4-pyridinecarboxylic acid is used as a key intermediate in the synthesis of various chemical compounds. Its unique structure, featuring a chlorinated and nitrated pyridine ring, allows for further chemical reactions and modifications, making it a valuable building block in the creation of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Chloro-3-nitro-4-pyridinecarboxylic acid is used as a starting material for the development of new drugs. Its chemical properties enable it to be a precursor for the synthesis of potential therapeutic agents, particularly those targeting central nervous system disorders, inflammation, or other conditions that may benefit from novel molecular structures.
Used in Agrochemical Production:
2-Chloro-3-nitro-4-pyridinecarboxylic acid is also utilized in the agrochemical sector as a component in the formulation of pesticides and herbicides. Its reactivity and structural features make it suitable for the creation of compounds that can effectively control pests and weeds, thereby contributing to improved crop yields and agricultural productivity.
Used in Research and Development:
In academic and industrial research settings, 2-Chloro-3-nitro-4-pyridinecarboxylic acid serves as a valuable compound for exploring new chemical reactions and understanding the properties of pyridine-based molecules. Its use in research can lead to the discovery of new applications and advancements in various scientific fields.

InChI:InChI=1S/C6H3ClN2O4/c7-5-4(9(12)13)3(6(10)11)1-2-8-5/h1-2H,(H,10,11)

Upstream product

• 6635-86-5 2-amino-4-methyl-3-nitropyridine 
• 21901-18-8 2-hydroxy-4-methyl-3-nitropyridine 
• 695-34-1 2-Amino-4-methylpyridine 
• 23056-39-5 2-chloro-3-nitro-4-methylpyridine 

Downstream Products

• 1379302-09-6 methyl 2-chloro-3-nitroisonicotinate 

Relevant academic research and scientific papers

1-CYANO-PYRROLIDINE DERIVATIVES AS INHIBITORS OF USP30.

The present invention relates to novel compounds and methods for the manufacture of inhibitors of deubiquitylatingenzymes (DUBs). In particular, the invention relates to the inhibition of ubiquitin C- terminal hydrolase 30 or Ubiquitin Specific Peptidase 30 (USP30). The invention further relates to the use of DUB inhibitors in the treatment of conditions involving mitochondrial dysfunction and cancer. Compounds of the invention include compounds having the formula (I) (I) or a pharmaceutically acceptable salt thereof, wherein R1, R 2, R 3, m, L and X are as defined herein.

BENZIMIDAZOLE AND IMADAZOPYRIDINE CARBOXIMIDAMIDE COMPOUNDS

The present disclosure provides indoleamine 2,3-dioxygenase 1 (IDOL) inhibitors of Formula I: or pharmaceutically acceptable salts thereof, in which X, L, n, m, R1, R2a, R2b, Rn, Rm, and Rt are as defined herein, as well as pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts thereof, and methods of using the same to treat conditions mediated by IDO1.

NITROGENATED HETEROCYCLIC COMPOUND

The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.

THE NITROPYRIDINYL ETHYLENEIMINE COMPOUND, THE PHARMACEUTICAL COMPOSITION CONTAINING IT, THE PREPARATION METHOD AND USE THEREOF

The present invention discloses a nitropyridinyl ethyleneimine compound as shown in the formula I and a preparation method of the same, as well as use of the compound in manufacture of a prodrug and in manufacture of a drug for treating a tumor.