- Synthesis of an unnatural anacardic acid analogue
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The unnatural E isomer of anacardic acid 7 has been synthesized employing the following key steps: Swern oxidation of a diastereoisomeric mixture of β-hydroxyphosphine oxides 13a/b to the corresponding ketone 14 followed by stereo-specific reduction to th
- Green, Ivan R.,Tocoli, Felismino E.
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p. 947 - 957
(2007/10/03)
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- Substrate specificity of regiospecific desaturation of aliphatic compounds by a mutant Rhodococcus strain.
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Substrate specificity of cis-desaturation of alipahtic compounds by resting cells of a mutant, Rhodococcus sp. strain KSM-MT66, was examined. Among substrates tested, the rhodococcal cells were able to convert n-alkanes (C13-C19), 1-chloroalkanes (C16 and C18), ethyl fatty acids (C14-C17) and alkyl (C1-C4) esters of palmitic acid to their corresponding unsaturated products of cis configuration. The products from n-alkanes and 1-chloroalkanes had a double bond mainly at the 9th carbon from their terminal methyl groups, and the products from acyl fatty acids had a double bond mainly at the 6th carbon from their carbonyl carbons.
- Koike,Takaiwa,Kimura,Inoue,Ito
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p. 1064 - 1066
(2007/10/03)
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- Cross-Coupling Reaction of Alkyl- or Arylboronic Acid Esters with Organic Halides Induced by Thallium(I) Salts and Palladium-Catalyst
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The cross-coupling reaction of alkylboronic acid esters with 1-alkenyl- or aryl halides is succesfully catalyzed by PdCl2 (dppf) or Pd(PPh3)4 in the presence of thallium(I) hydroxide or carbonate to give the corresponding alkenes or arenes in good yields.The coupling reaction of arylboronic acid esters with aryl halides under similar conditions to provide biaryls is also described.
- Sato, Makoto,Miyaura, Norio,Suzuki, Akira
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p. 1405 - 1408
(2007/10/02)
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