Welcome to LookChem.com Sign In|Join Free

CAS

  • or
AC-ALA-AMC, also known as N-acetyl-Ala-AMC or N-acetyl-L-alanine-7-amido-4-methylcoumarin, is a fluorogenic substrate specifically designed for the detection and quantification of protease activity. This synthetic peptide incorporates the amino acid alanine and a fluorophore, 7-amino-4-methylcoumarin, which becomes fluorescent upon proteolytic cleavage. The fluorescence emitted can be measured, offering a sensitive and convenient method for protease activity studies. AC-ALA-AMC is widely utilized in research and drug discovery, serving as a valuable tool for investigating the roles of proteases in physiological and pathological processes.

355137-87-0 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 355137-87-0 Structure
  • Basic information

    1. Product Name: AC-ALA-AMC
    2. Synonyms: ACETYL-L-ALANINE 7-AMIDO-4-METHYLCOUMARIN;AC-ALA-AMC;AC-ALANINE-AMC;N-ALPHA-ACETYL-L-ALANINE 7-AMIDO-4-METHYLCOUMARIN
    3. CAS NO:355137-87-0
    4. Molecular Formula: C15H16N2O4
    5. Molecular Weight: 288.3
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 355137-87-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: -15°C
    8. Solubility: N/A
    9. CAS DataBase Reference: AC-ALA-AMC(CAS DataBase Reference)
    10. NIST Chemistry Reference: AC-ALA-AMC(355137-87-0)
    11. EPA Substance Registry System: AC-ALA-AMC(355137-87-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 355137-87-0(Hazardous Substances Data)

355137-87-0 Usage

Uses

Used in Research Applications:
AC-ALA-AMC is used as a detection tool for monitoring the activity of proteases such as trypsin and chymotrypsin. Its application is crucial for understanding the function of these enzymes in various biological systems.
Used in Drug Discovery:
AC-ALA-AMC is used as a screening agent to identify and characterize inhibitors of proteases. This application aids in the development of potential therapeutic agents targeting protease activity in diseases where proteases play a significant role.
Used in Enzymatic Assays:
In the field of biochemistry, AC-ALA-AMC is used as a substrate in enzymatic assays to measure the activity of specific proteases. The fluorescence resulting from the cleavage of the substrate provides a quantitative assessment of protease activity, which is essential for studying enzyme kinetics and mechanisms.
Used in Pathological Studies:
AC-ALA-AMC is used as a diagnostic and research tool in the study of pathological processes where proteases are implicated. This includes conditions such as cancer, where proteases can contribute to tumor progression and metastasis, and inflammatory diseases, where protease activity can lead to tissue damage.
Used in Pharmaceutical Development:
In the pharmaceutical industry, AC-ALA-AMC is used to evaluate the efficacy of protease inhibitors as potential drugs. This application is vital for the development of new treatments targeting protease-mediated diseases.
Overall, AC-ALA-AMC is a versatile and essential compound in the fields of molecular biology, biochemistry, and medicine, providing researchers with a reliable method to study and modulate protease activity.

Check Digit Verification of cas no

The CAS Registry Mumber 355137-87-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,5,1,3 and 7 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 355137-87:
(8*3)+(7*5)+(6*5)+(5*1)+(4*3)+(3*7)+(2*8)+(1*7)=150
150 % 10 = 0
So 355137-87-0 is a valid CAS Registry Number.

355137-87-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2-acetamido-N-(4-methyl-2-oxochromen-7-yl)propanamide

1.2 Other means of identification

Product number -
Other names Acetyl-L-alanine 7-amido-4-methylcoumarin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:355137-87-0 SDS

355137-87-0Upstream product

355137-87-0Downstream Products

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 355137-87-0