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5-{[4-(1-piperidinylsulfonyl)phenyl]hydrazono}-2,4,6(1H,3H,5H)-pyrimidinetrione is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 5-{[4-(1-piperidinylsulfonyl)phenyl]hydrazono}-2,4,6(1H,3H,5H)-pyrimidinetrione

    Cas No: 355411-86-8

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  • 355411-86-8 Structure
  • Basic information

    1. Product Name: 5-{[4-(1-piperidinylsulfonyl)phenyl]hydrazono}-2,4,6(1H,3H,5H)-pyrimidinetrione
    2. Synonyms: 5-{[4-(1-piperidinylsulfonyl)phenyl]hydrazono}-2,4,6(1H,3H,5H)-pyrimidinetrione;5-{2-[4-(piperidin-1-ylsulfonyl)phenyl]hydrazinylidene}pyrimidine-2,4,6(1H,3H,5H)-trione
    3. CAS NO:355411-86-8
    4. Molecular Formula: C15H17N5O5S
    5. Molecular Weight: 379.39098
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 355411-86-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-{[4-(1-piperidinylsulfonyl)phenyl]hydrazono}-2,4,6(1H,3H,5H)-pyrimidinetrione(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-{[4-(1-piperidinylsulfonyl)phenyl]hydrazono}-2,4,6(1H,3H,5H)-pyrimidinetrione(355411-86-8)
    11. EPA Substance Registry System: 5-{[4-(1-piperidinylsulfonyl)phenyl]hydrazono}-2,4,6(1H,3H,5H)-pyrimidinetrione(355411-86-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 355411-86-8(Hazardous Substances Data)

355411-86-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 355411-86-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,5,4,1 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 355411-86:
(8*3)+(7*5)+(6*5)+(5*4)+(4*1)+(3*1)+(2*8)+(1*6)=138
138 % 10 = 8
So 355411-86-8 is a valid CAS Registry Number.

355411-86-8Downstream Products

355411-86-8Relevant articles and documents

Synthesis, activity evaluation, and docking analysis of barbituric acid aryl hydrazone derivatives as RSK2 inhibitors

Xue, Mengzhu,Xu, Minghao,Lu, Weiqiang,Huang, Jin,Li, Honglin,Xu, Yufang,Liu, Xiaofeng,Zhao, Zhenjiang

, p. 747 - 752 (2013/07/26)

The 90 kDa ribosomal S6 kinases (RSKs), especially RSK2, have attracted attention for the development of new anticancer agents. Through structural optimization of the hit compound 1 from our previous study, a series of barbituric acid aryl hydrazone analogues were designed and synthesized as potential RSK2 inhibitors. The most potent one, compound 9, showed a higher activity against RSK2 with an IC50 value of 1.95 μM. To analyze and elucidate their structure-activity relationship, the homology model of RSK2 N-terminal kinase domain was built and molecular docking simulations were performed, which provide helpful clues to design new inhibitors with desired activities.

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