35588-53-5

Basic information

• Product Name: [4-(METHYLTHIO)PHENYL]HYDRAZINE HYDROCHLORIDE
• Synonyms: (4-METHYLSULFANYLPHENYL)HYDRAZINE HYDROCHLORIDE;[4-(METHYLTHIO)PHENYL]HYDRAZINE HYDROCHLORIDE;1-(4-(Methylthio)phenyl)hydrazine hydrochloride;4-Hydrazinothioanisole hydrochloride, 4-Hydrazinophenyl methyl sulphide hydrochloride;4-(Methylsulphanyl)phenylhydrazinehydrochloride
• CAS NO: 35588-53-5
• Molecular Formula: C7H11ClN2S
• Molecular Weight: 190.69
• Mol File: 35588-53-5.mol

Chemical Properties

• Melting Point: 197(dec.)
• Boiling Point: 305.7°Cat760mmHg
• Flash Point: 138.7°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.000806mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: [4-(METHYLTHIO)PHENYL]HYDRAZINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(METHYLTHIO)PHENYL]HYDRAZINE HYDROCHLORIDE(35588-53-5)
• EPA Substance Registry System: [4-(METHYLTHIO)PHENYL]HYDRAZINE HYDROCHLORIDE(35588-53-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 35588-53-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Discovery:
[4-(METHYLTHIO)PHENYL]HYDRAZINE HYDROCHLORIDE is used as a key intermediate in the synthesis of pharmaceuticals for its potential biological activities, contributing to the development of new drugs with therapeutic benefits.
Used in Antitumor and Antiviral Applications:
In the medical field, [4-(METHYLTHIO)PHENYL]HYDRAZINE HYDROCHLORIDE is studied for its potential as an antitumor agent, targeting the inhibition of tumor growth, and as an antiviral agent, aiming to combat viral infections.
Used in Organic Chemical Reactions:
As a reagent in organic chemistry, [4-(METHYLTHIO)PHENYL]HYDRAZINE HYDROCHLORIDE is used for the formation of carbon-nitrogen bonds, which are crucial in creating a variety of organic compounds and molecules.
Used in Chemical Synthesis Industry:
[4-(METHYLTHIO)PHENYL]HYDRAZINE HYDROCHLORIDE is used as a building block in the synthesis of various organic compounds, playing a significant role in the creation of new chemical entities for diverse applications.

InChI:InChI=1/C7H10N2S/c1-10-7-4-2-6(9-8)3-5-7/h2-5,9H,8H2,1H3

Upstream product

• 104-96-1 4-methylsulfanylaniline 
• 104-95-0 (4-bromophenyl)thioanisole 
• 18620-04-7 4-thioanisolemagnesium bromide 
• 115171-09-0 N,N'-bis-(t-butoxycarbonyl)-4-(methylthio)phenylhydrazine 

Downstream Products

• 847233-92-5 3-(4-chlorophenoxy)-2-methyl-5-(methylsulfonyl)-1H-indole-1-acetic acid methyl ester 
• 847233-91-4 3-(4-chlorophenoxy)-2-methyl-5-(methylthio)-1H-indole-1-acetic acid methyl ester 
• 96869-27-1 2-(2-(1-(3,4-dichlorobenzyl)-2-methyl-5-(methylthio)-1H-indol-3-yl)ethyl)isoindoline-1,3-dione 
• 96868-66-5 2-(2-(1-benzyl-2-methyl-5-(methylthio)-1H-indol-3-yl)ethyl)isoindoline-1,3-dione 
• 1383843-39-7 1,3-bis(4-chlorobenzyl)-2-methyl-5-(methylthio)-1H-indole 

Relevant articles and documents

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3-hetero-substituted-n-benzyl-indoles and prevention of leucotriene synthesis therewith

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Aryllithiums and arylmagnesium bromides add to the N=N bond of di-t-butyl azodicarboxylate, and subsequent acid deprotection provides the arylhydrazine.