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N-(4-cyanophenyl)butanamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 356100-65-7 Structure
  • Basic information

    1. Product Name: N-(4-cyanophenyl)butanamide
    2. Synonyms: N-(4-cyanophenyl)butanamide
    3. CAS NO:356100-65-7
    4. Molecular Formula: C11H12N2O
    5. Molecular Weight: 188.22578
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 356100-65-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(4-cyanophenyl)butanamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(4-cyanophenyl)butanamide(356100-65-7)
    11. EPA Substance Registry System: N-(4-cyanophenyl)butanamide(356100-65-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 356100-65-7(Hazardous Substances Data)

356100-65-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 356100-65-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,6,1,0 and 0 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 356100-65:
(8*3)+(7*5)+(6*6)+(5*1)+(4*0)+(3*0)+(2*6)+(1*5)=117
117 % 10 = 7
So 356100-65-7 is a valid CAS Registry Number.

356100-65-7Downstream Products

356100-65-7Relevant articles and documents

Nickel-Catalyzed Cyanation of Aryl Thioethers

Delcaillau, Tristan,Woenckhaus-Alvarez, Adrian,Morandi, Bill

supporting information, p. 7018 - 7022 (2021/09/13)

A nickel-catalyzed cyanation of aryl thioethers using Zn(CN)2 as a cyanide source has been developed to access functionalized aryl nitriles. The ligand dcype (1,2-bis(dicyclohexylphosphino)ethane) in combination with the base KOAc (potassium acetate) is essential for achieving this transformation efficiently. This reaction involves both a C-S bond activation and a C-C bond formation. The scalability, low catalyst and reagents loadings, and high functional group tolerance have enabled both late-stage derivatization and polymer recycling, demonstrating the reaction's utility across organic chemistry.

Practical one-pot amidation of N -Alloc-, N -Boc-, and N -Cbz protected amines under mild conditions

Hong, Wan Pyo,Tran, Van Hieu,Kim, Hee-Kwon

, p. 15890 - 15895 (2021/05/19)

A facile one-pot synthesis of amides from N-Alloc-, N-Boc-, and N-Cbz-protected amines has been described. The reactions involve the use of isocyanate intermediates, which are generated in situ in the presence of 2-chloropyridine and trifluoromethanesulfonyl anhydride, to react with Grignard reagents to produce the corresponding amides. Using this reaction protocol, a variety of N-Alloc-, N-Boc-, and N-Cbz-protected aliphatic amines and aryl amines were efficiently converted to amides with high yields. This method is highly effective for the synthesis of amides and offers a promising approach for facile amidation.

Convenient metal-free direct oxidative amidation of aldehyde using dibromoisocyanuric acid under mild conditions

Kang, Soosung,La, Minh Thanh,Kim, Hee-Kwon

supporting information, p. 3541 - 3546 (2018/08/29)

A facile method for the direct synthesis of amides from aldehydes is described. Amide bonds were synthesized by an oxidative amidation in the presence of dibromoisocyanuric acid (DBI). Treatment of aromatic and aliphatic aldehydes with dibromoisocyanuric acid generated acyl bromide intermediates, which were employed to react with a variety of secondary and primary amines to give amides. Through this reaction method, various amides were synthesized directly from aldehydes under mild conditions in high yields and short times. This facile and efficient procedure provides potential strategy for the direct synthesis of amides from aldehydes.

Catalyst- and Supporting-Electrolyte-Free Electrosynthesis of Benzothiazoles and Thiazolopyridines in Continuous Flow

Folgueiras-Amador, Ana A.,Qian, Xiang-Yang,Xu, Hai-Chao,Wirth, Thomas

supporting information, p. 487 - 491 (2017/12/15)

A catalyst- and supporting electrolyte-free method for electrochemical dehydrogenative C?S bond formation in continuous flow has been developed. A broad range of N-arylthioamides have been converted to the corresponding benzothiazoles in good to excellent yields and with high current efficiencies. This transformation is achieved using only electricity and laboratory grade solvent, avoiding degassing or the use of inert atmosphere. This work highlights three advantages of electrochemistry in flow, which is (i) a supporting electrolyte-free reaction, (ii) an easy scale-up of the reaction without the need for a larger reactor and, (iii) the important and effective impact of having a good mixing of the reaction mixture, which can be achieved effectively with the use of flow systems. This clearly improves the reported methods for the synthesis of benzothiazoles.

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