cas 356560-80-0, 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE

Articles about 356560-80-0Total 16 be found

Novel pyridinyl triazolopyridine derivatives and use thereof
The present invention relates to novel pyridinyl-triazolopyridine derivatives and uses thereof, and more specifically, to an aromatic organic material including pyrimidine and an organic electroluminescent device using the same. According to an embodiment of the present invention, the organic electroluminescent device using the aromatic organic material including the pyrimidine can obtain light at a short wavelength in a highly efficient manner while lowering the driving voltage.COPYRIGHT KIPO 2019
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(2019/01/30)

AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES
The present invention relates to certain amido-benzyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.
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Page/Page column 141

(2013/09/12)

PYRIDINYL AND PYRIMIDINYL SULFOXIDE AND SULFONE DERIVATIVES
Disclosed are certain pyridinyl and pyrimidinyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds and methods of treatment using such compounds.
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Page/Page column 92

(2013/09/12)

AMIDO-BENZYL SULFONE AND SULFONAMIDE DERIVATIVES
Disclosed are certain amido-benzyl sulfone and sulfonamide compounds, pharmaceutical compositions comprising such compounds, land methods of treatment using such compounds.
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Page/Page column 67

(2013/09/12)

AMIDO-BENZYL SULFOXIDE DERIVATIVES
The present invention relates to certain amido-benzyl sulfoxide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment of an NAMPT-mediated disease or condition in a subject, selected from solid or liquid tumor, rheumat
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Paragraph 0206

(2013/09/12)

ALKYL-AND DI-SUBSTITUTED AMIDO-BENZYL SULFONAMIDE DERIVATIVES
The present invention relates to certain alkyl- and di-substituted amido-benzyl sulfonamide compounds, pharmaceutical compositions comprising such compounds, and to methods of treatment of NAMPT-mediated disorders, such as diabetes, rheumatoid arthritis,
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Paragraph 0214

(2013/09/12)

SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF
The present application relates to novel substituted 5-aminopyrazoles, methods of production thereof, use thereof alone or in combinations for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or prophylaxis of diseases.
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Page/Page column 87

(2010/04/03)

CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
Novel [1,2,4]triazolo[1,5-a]pyridinyl-6-yl-substituted tetrahydroisoquinolines are described in the present invention. These compounds and crystalline forms SA1 and N-2 are used in the treatment of various neurological and physiological disorders. Methods of making these compounds and crystalline forms SA-1 and N-2 are also described in the present invention.
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Page/Page column 39

(2010/12/17)

ARYL, HETEROARYL, AND HETEROCYCLE SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF
Novel aryl, heteroaryl, and non-aromatic heterocyle substituted tetrahydroisoquinolines are described in the present invention. These compounds are used in the treatment of various neurological and physiological disorders. Methods of making these compounds are also described in the present invention.
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Page/Page column 109

(2010/12/17)

7-([1,2,4,]TRIAZOLO[1,5,-A]PYRIDIN-6-YL)-4-(3,4-DICHLOROPHENYL)-1,2,3,4- TETRAHYDROISOQUINOLINE AND USE THEREOF
Novel [l,2,4]triazolo[l,5-α]pyridinyl-6-yl-substituted tetrahydroisoquinolines are described in the present invention. These compounds and crystalline forms SAl and N-2 are used in the treatment of various neurological and physiological disorders. Methods of making these compounds and crystalline forms SA-I and N-2 are also described in the present invention.
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Page/Page column 38

(2010/12/17)

(2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1, 2,4]triazolo[1,5-a]-pyridin-6-ylphenyl)butanamide: A selective α-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
A series of β-substituted biarylphenylalanine amides were synthesized and evaluated as inhibitors of dipeptidyl peptidase IV (DPP-4) for the treatment of type 2 diabetes. Optimization of the metabolic profile of early analogues led to the discovery of (2S
Edmondson, Scott D.,Mastracchio, Anthony,Mathvink, Robert J.,He, Jiafang,Harper, Bart,Park, You-Jung,Beconi, Maria,Di Salvo, Jerry,Eiermann, George J.,He, Huaibing,Leiting, Barbara,Leone, Joseph F.,Levorse, Dorothy A.,Lyons, Kathryn,Patel, Reshma A.,Patel, Sangita B.,Petrov, Aleksandr,Scapin, Giovanna,Shang, Jackie,Roy, Ranabir Sinha,Smith, Aaron,Wu, Joseph K.,Xu, Shiyao,Zhu, Bing,Thornberry, Nancy A.,Weber, Ann E.
p. 3614 - 3627
(2007/10/03)

CYCLOHEXYLALANINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
The present invention is directed to novel cyclohexylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
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Page/Page column 66

(2010/02/15)

New method for the general synthesis of [1,2,4]triazolo[1,5-a]pyridines
[1,2,4]Triazolo[1,5-a]pyridines without substituants on the 2-position have been prepared from 2-aminopyridines by cyclization of N-(pyrid-2-yl) formamidoximes with trifluoroacetic anhydride. Triazoles substituted at any position on the pyridine ring may be prepared in good yields and under mild reaction conditions. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.
Huntsman, Elliott,Balsells, Jaume
p. 3761 - 3765
(2007/10/03)

PHENYLALANINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
The present invention is directed to phenylalanine derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
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Page 84

(2010/02/07)

Pyridinylimidazoles
Compounds of formula (I) and pharmaceutically acceptable salts thereof wherein R1, R2 and R3 represent various functional groups, and one of X1 and X2 is N and the other is NR10; and their
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(2008/06/13)