357263-48-0

Basic information

• Product Name: 7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE
• Synonyms: 7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE;7-Chloro-4-azaindole;7-Chloro-4-azaindole 7-;7-Chloro-1H-pyrrolo[3,2-b...;7-chloro-1H-pyrrolo[3
• CAS NO: 357263-48-0
• Molecular Formula: C₇H₅ClN₂
• Molecular Weight: 152.58
• Product Categories: Azaindoles
• Mol File: 357263-48-0.mol

Chemical Properties

• Boiling Point: 290.572 °C at 760 mmHg
• Flash Point: 157.181 °C
• Appearance: /
• Density: 1.425
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.703
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 13.08±0.40(Predicted)
• CAS DataBase Reference: 7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE(357263-48-0)
• EPA Substance Registry System: 7-CHLORO-1H-PYRROLO[3,2-B]PYRIDINE(357263-48-0)

Safety Data

• Hazardous Substances Data: 357263-48-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
7-Chloro-1H-pyrrolo[3,2-b]pyridine is used as an intermediate in the synthesis of pharmaceutical drugs. Its unique structure and reactivity allow for the development of new and effective medications.
Used in Agrochemical Industry:
7-Chloro-1H-pyrrolo[3,2-b]pyridine is used as a building block in the creation of agrochemical products. Its properties contribute to the development of innovative and efficient solutions for agricultural applications.
Used in Organic Chemistry Research:
7-Chloro-1H-pyrrolo[3,2-b]pyridine serves as a substrate in various organic chemistry reactions, enabling researchers to explore new reaction pathways and synthesize novel compounds with potential applications in various fields.
Used in Drug Development:
Due to its unique structure, 7-chloro-1H-pyrrolo[3,2-b]pyridine is utilized in the research and development of new drugs. Its reactivity and potential to form various derivatives make it a valuable component in the drug discovery process.

InChI:InChI=1/C7H5ClN2/c8-5-1-3-9-6-2-4-10-7(5)6/h1-4,10H

Upstream product

• 5435-54-1 4-hydroxy-3-nitropyridine 

Downstream Products

• 425380-39-8 7-methoxy-1H-pyrrolo[3,2-b]pyridine 
• 875340-60-6 7-(2-fluoro-4-nitrophenoxy)-1H-pyrrolo[3,2-b]pyridine 
• 1547041-34-8 7-chloro-1-methyl-1H-pyrrolo[3,2-b]pyridine 

Relevant articles and documents

AKT PROTEIN KINASE INHIBITORS

The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.