358721-33-2

Basic information

• Product Name: Apocynol A
• Synonyms: Apocynol A;(4R)-4-[(1E,3R)-3-Hydroxy-1-buten-1-yl]-3-(hydroxymethyl)-5,5-dimethyl-2-cyclohexen-1-one
• CAS NO: 358721-33-2
• Molecular Formula: C13H20O3
• Molecular Weight: 224.2961
• Mol File: 358721-33-2.mol

Chemical Properties

• Boiling Point: 377.1±42.0 °C(Predicted)
• Appearance: /
• Density: 1.113±0.06 g/cm3(Predicted)
• PKA: 14.28±0.20(Predicted)
• CAS DataBase Reference: Apocynol A(CAS DataBase Reference)
• NIST Chemistry Reference: Apocynol A(358721-33-2)
• EPA Substance Registry System: Apocynol A(358721-33-2)

Safety Data

• Hazardous Substances Data: 358721-33-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Apocynol A is used as an anti-cancer agent for its ability to inhibit the growth of cancer cells in various types of cancer, such as breast and lung cancer. Its potential in this application is attributed to its direct effects on tumor growth and the modulation of oncological signaling pathways.
Used in Antioxidant and Anti-inflammatory Applications:
Apocynol A is used as a therapeutic agent for its antioxidant and anti-inflammatory properties, which may contribute to the treatment and management of various diseases and conditions where oxidative stress and inflammation play a significant role.
Used in Drug Development Research:
Apocynol A is used as a subject of research for the development of new drugs, given its potential in cancer treatment and other therapeutic areas. Ongoing studies aim to elucidate its mechanisms of action and assess its safety and efficacy for clinical use.

Relevant articles and documents

Glochidionionosides A-D: Megastigmane glucosides from leaves of Glochidion zeylanicum (Gaertn.) A. Juss

Five megastigmane glucosides were isolated from the leaves of Glochidion zeylanicum. One of them was a known compound, blumenol C O-β-D- glucopyranoside (1), and the structures of the four new compounds, glochidionionosides A-D (2-5), were mainly elucidated by spectroscopic methods, including a modified Mosher's method. The absolute configurations of the six-membered ring of glochidionionoside D (5) were deduced by β-D-glucopyranosylation-induced shift trends in the 13C-NMR spectra and confirmed by X-ray analysis as its pbromobenzoate (5b), and the axis chirality of C-7 was determined to be R.

Medicinal foodstuffs. XXIV. Chemical constituents of the processed leaves of Apocynum venetum L.: Absolute stereostructures of apocynosides I and II

Two new ionone glucosides, named apocynosides I and II, were isolated from the roasted leaves of Apocynum venetum L. together with nine known compounds. The absolute stereostructures of apocynosides I and II were determined by chemical and physicochemical evidence, which included the application of a modified Mosher's method and the circular dichroism helicity rule.