- SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS
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This invention is directed to spiro-oxindole compounds, as stereoisomers, enantiomers, tautomers thereof or mixtures thereof; or pharmaceutically acceptable salts, solvates or prodrugs thereof, for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.
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Page/Page column 152; 153
(2010/04/30)
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- Synthesis of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives as potential beta-3-adrenergic receptor ligands (part 2)
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Adrenoceptors beta-3-subtype mediate lipolysis and in the search for potential beta-3-adrenergic receptors agonists for the treatment of obesity, we designed new arylethanolamines (structures 4, 5) and aryloxypropanolamines (structures 6, 7) derived from 2(3H)-benzoxazolone and 2(3H)-benzothiazolone.
- Delhomel,Yous,Depreux,Lesieur
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p. 633 - 639
(2007/10/03)
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